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  • 1
    Electronic Resource
    Electronic Resource
    Platelet-rich plasma serotonin levels in tension-type headache and depression (1993)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 13 (1993), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We measured platelet-rich plasma (PRP) serotonin in patients suffering from tension-type headache, before and after treatment with amitriptyline, comparing them with a healthy control group and patients with untreated depression. We evaluated the severity of headache and depression in each group. PRP serotonin levels were higher in patients with headache than in controls and depressed patients. We observed a fall of PRP serotonin in patients with tension-type headache to similar levels after treatment as the depressed group. This fall was correlated with the improvement of headache but not with depression scales. Our data suggest that the rise of platelet serotonin levels in tension-type headache is related to pain and not depression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1993.1305346.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Neuroexcitatory amino acid levels in plasma and cerebrospinal fluid during migraine attacks (1993)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 13 (1993), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A current hypothesis for migraine suggests that neuroexcitatory amino acids may participate in the triggering of attacks. To investigate this possibility we measured glutamic and aspartic acid level in plasma and cerebrospinal fluid (CSF) of patients with common and classic migraine during attacks, making comparisons with controls suffering from stress. Plasma levels of amino acids in migraine patients were lower than in controls. CSF concentrations of glutamic acid were higher in migraineurs than in controls. Our results suggest an excess of neuroexcitatory amino acids in the CNS of migraine patients during attacks, possibly favoring a state of neuronal hyperexcitability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1993.1302089.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Adherence and invasive capacities of the fish pathogen Pasteurella piscicida (1996)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 138 (1996), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Pasteurella piscicida strains were weakly or moderately adherent to cell lines, the levels of attachment being variable depending on the cells employed. All the isolates exhibited the highest binding capacity to CHSE-214 cells. Adhesive capacities were affected by heat and sugars but not by proteinase K or by treatment with antisera raised against the lipopolysaccharides of P. piscicida, implicating components of glycoprotein(s) as ligands in the adhesion process. The isolates showed a great binding capacity to intestines from the marine fish hosts gilthead sea bream, sea bass and turbot, with values ranging from 104 to 105 bacteria/g. Although the P. piscicida strains showed a weak invasiveness in the poikilothermic cell lines employed as in vitro model, the bacteria remained viable inside the infected cells at least for 2 days. The invasion process was inhibited by cytochalasin D indicating the active participation of the host cell cytoskeleton in the internalization of P. piscicida.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1996.tb08130.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Response of eosinophilic granule cells of gilthead seabream (Sparus aurata, Teleostei) to bacteria and bacterial products (1996)
    Springer
    Cell & tissue research 287 (1996), S. 223-230 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Eosinophilic granule cell ; Phagocytosis ; Cytochemistry ; Gill ; Peritoneal exudate ; Extracellular products ; Sparus aurata (Teleostei)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Eosinophilic granule cells in the gills and peritoneal exudate of gilthead seabream (Sparus aurata L.) are characterized by the presence of prominent eosinophilic granules in their cytoplasm and are here described for the first time. The oval granules of these cells contain an electron-dense inclusion surrounded by a less dense filamentous matrix and are peroxidase- and acid phosphatase-negative. Unlike other granulocytes of gilthead seabream, eosinophilic granule cells do not ingest bacteria in vivo. The intraperitoneal injection of extracellular products of Pasteurella piscicida induces mobilization of eosinophilic granule cells to the blood and other tissues and causes changes in their structure. Shortly after injection, the granules of eosinophilic granule cells become swollen and some fuse with the cell membrane. From 7 h post-injection, many eosinophilic granule cells in the gills degenerate and are then phagocytosed by macrophages, which are especially abundant after 24 h. From 24 h to 72 h, eosinophilic granule cells from the gills contain abundant autolysosomes together with granules of a normal morphology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004410050748
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    Paper (German National Licenses)
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