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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 192 (1961), S. 868-870 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] This communication deals with the metabolism of propionate by whole homogenates of sheep liver, prepared to retain mitochondrial respiration. Measurements were made of the rate of consumption of propionate and the rate of uptake of oxygen. In addition, the nature of the products of propionate ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 26 (1976), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Mitochondria from the cerebral cortex of untreated lambs from areas in which enzootic ataxia occurred showed a lower content of haem a (from cytochromes a and a 3) than mitochondria from control lambs with adequate copper but the haems of cytochromcs b2 c1 and c were not depleted. Cytochrome oxidase activity was closely correlated with the content of haem a (P〈0.001) but there was no correlation with total mitochondrial copper which was always present in molar exccss of haem a. It is concluded that the lowered cytochrome oxidase activity in mitochondria from untreated lambs is immediately attributable to depletion of haem a. In clinically ataxic lambs that showed degradation of myelin in thc spinal cord, brain cytochrome oxidase was depressed by no more t han 60%. Arguments are advanced that this depletion was not sufficiently severe to have led to respiratory constraint
    Type of Medium: Electronic Resource
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