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  • 1
    Electronic Resource
    Electronic Resource
    Favourable levels of cardio-vascular health and risk indicators during childhood and adolescence (1985)
    Springer
    European journal of pediatrics 144 (1985), S. 360-367 
    Details
    ISSN: 1432-1076
    Keywords: Cardio-vascular health indicators ; Maximal aerobic power ; Arterial blood pressure ; Blood lipids ; Habitual physical activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper is concerned with favourable levels of constitutional cardio-vascular health indicators during childhood and adolescence. A cross-sectional randomised sample of healthy Czechoslovakian children was investigated, because this population is habituated to a favourable life style. Twenty girls and 20 boys at ages 8, 12 and 16 years were recruited to the study. Statistical data for means and standard deviations are presented with regard to maximal aerobic power, haemodynamic variables such as arterial blood pressure, heart rate at submaximal and maximal muscular exercise, body fat content, blood lipids including total cholesterol and its fractions, high- and low-density lipo-proteins, fasting triglycerides and the apo-lipo-protein profile. The maximal oxygen uptake in absolute values increased with age in both sexes and the boys appeared to average higher than the girls at each age. When maximal aerobic power was expressed on a total body weight basis, boys appeared to average higher at age 16 years (56 ml·min-1·kg-1) than girls (45.8 ml·min-1·kg-1). The highest recorded heart rate for ergometric work averaged close to 200 min-1 in both sexes with no significant age differences. The diastolic blood pressure at rest did not change significantly with age or sex. Serum cholesterol levels were found to decrease significantly after puberty in boys (post-pubertal dip), but in the girls there was found no systematic change in mean values with age. When HDL was expressed as a percentage of total cholesterol there appeared to be no differences related to age and sex. Neither the apo-lipo-proteins, nor the fasting serum triglycerides changed significantly with age and sex. The inter-relationship between the different health indicators as well the influences of life style on risk factors are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441778
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Working ability and exercise tolerance during treatment of a mild hypertension (1985)
    Springer
    International archives of occupational and environmental health 56 (1985), S. 41-47 
    Details
    ISSN: 1432-1246
    Keywords: Working ability ; Mild hypertension ; Atenolol ; Nifedipine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A randomized cross-over trial was undertaken on 21 occupationally active persons who had a stable mild or moderate hypertension with the purpose of comparing the effect of a beta-adreno-receptor blocking agent (atenolol) with that of a calcium channel inhibitor (nifedipine). The doses recommended by the manufactures were used. Atenolol (100 mg) given once a day resulted in a marked hypotensive effect at rest as well as during exercise, the compliance was satisfactory, and the hemodynamic changes were not reflected in unfavourable side effects during muscular exercise or in the subjects own personal assessment of fatigue during the exercise tests which ranged in energy expenditure from about three to six times the resting level. However, unfavourable, modest side effects occurred in two subjects during atenolol medication to the extent that they wanted to terminate the study. Nifedipine therapy with doses of 10 mg, three times a day, resulted in a modest, but statistically insignificant reduction in arterial blood pressure, which contrasts with previous published results. It is suggested that the modest effect is caused or related to the poor compliance and a daily dose that was quantitatively too small. No unfavourable side effects were seen during muscular efforts when the subjects were on nifedipine medication.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00380699
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Working ability and exercise tolerance during treatment of mild hypertension (1985)
    Springer
    International archives of occupational and environmental health 56 (1985), S. 49-55 
    Details
    ISSN: 1432-1246
    Keywords: Mild hypertension ; Working ability ; Atenolol ; Prazosin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The treatments of mild hypertension with atenolol and prazosin in occupationally active men and women were compared in a double blind cross-over with placebo. The hypotensive effect of the beta-adreno-receptor blocking drug, atenolol, were striking and in accordance with current knowledge, using one daily dose of 100 mg. In contrast, the hypotensive effect of taking 2 mg prazosin twice a day was modest, averaging about 3% when compared with placebo, somewhat less but still detectable during the performance of muscular exercises. Atenolol medication significantly reduced heart rate and blood pressure responses to muscular exercises, covering a range of work loads experienced during ordinary working days. No increased feeling of muscular fatigue or other discomfort during muscular work compared to that on prazosin and placebo medication could be detected. It was therefore concluded that atenolol medication was a useful treatment of mild hypertension and did not reduce the normal working ability and exercise tolerance. Prazosin medication did not significantly change working ability and exercise tolerance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00380700
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Comparison of two analytical procedures for the determination of free urinary catecholamines under the demands of shiftwork experiments (1988)
    Springer
    International archives of occupational and environmental health 61 (1988), S. 89-93 
    Details
    ISSN: 1432-1246
    Keywords: Shiftwork ; Noradrenaline ; Adrenaline ; Automated analysis ; Validation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A typical shiftwork experiment was chosen to prove the validity of an automated procedure for the analysis of free noradrenaline and adrenaline in urine. The method consists of a column switching technique with an adsorption/elution clean-up and a reversed phase high performance liquid chromatography followed by chemical reaction detection based on the trihydroxyindole method. The analysis of variance was performed using a second data set obtained by a semi-automated procedure for which the accuracy had already been confirmed. The analysis of covariance showed that for field studies, as well as for laboratory experiments in which the variances contributed by the experiments themselves are greater than 10% rel., the data sets of the two methods provide the same information.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00381612
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Leisure time sport activities and maximal aerobic power during late adolescence (1984)
    Springer
    European journal of applied physiology 52 (1984), S. 431-436 
    Details
    ISSN: 1439-6327
    Keywords: Habitual physical activity ; Adolescence ; Maximal aerobic power
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pattern of leisure time sport activity was estimated by retrospective recalls and expressed in terms of an annual sport activity score. The activity score was related to the development of maximal aerobic power during the period of late adolescence in German children. Both girls and boys reduced their activity pattern from 14 to 18 years of age, boys more than girls. At each age boys were more active than girls. A slight tendency towards better fitness with increased habitual physical activity was noticed, but many sedentary children exhibited a good performance capacity and some children with a high level of leisure time sport activity were characterized by a low level of maximal aerobic power. A statistical analysis revealed that the observed tendency to better fitness with increased habitual physical activity could be explained by an age factor with no additional effect of variation in sport activity score.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00943375
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    Paper (German National Licenses)
    Fulltext
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