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  • 1
    Electronic Resource
    Electronic Resource
    Should all patients with malignant astrocytoma have postoperative radiotherapy? (1991)
    Springer
    Acta neurochirurgica 108 (1991), S. 15-21 
    Details
    ISSN: 0942-0940
    Keywords: Malignant astrocytoma ; radiotherapy ; prognostic factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A retrospective analysis was carried out on 96 patients with malignant astrocytoma treated during the period 1977–1986 to evaluate the contribution of postoperative radiation treatment to survival. In this material the initial Karnofsky performance score, age and extent of resection appeared to be prognostic factors, on the basis of which suggestions are given for selection of patients for radiotherapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01407661
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Letter to the editor (1992)
    Springer
    Acta neurochirurgica 119 (1992), S. 176-177 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01541806
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Adult adrenoleukodystrophy: the clinical spectrum in a large Dutch family (1992)
    Springer
    Journal of neurology 239 (1992), S. 107-111 
    Details
    ISSN: 1432-1459
    Keywords: Adrenoleukodystrophy ; Very long chain fatty acids ; Carrier detection ; Adrenocortical function ; Cerebral sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A large family with adrenoleukodystrophy is described and the case histories of two clinically symptomatic and related male patients are presented. Clinical, biochemical and genetic screening of their family demonstrated two clinically affected males, one biochemically affected male and five carrier females. Two women were symptomatic; one suffered an acute exacerbation. One female was diagnosed as a carrier, based on genetic analysis and the family history only. Endocrinological screening was performed in the five affected males, demonstrating an elevated adrenocorticotrophic hormone level and a normal cortisol level in two, as evidence of compensated adrenocortical failure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00862985
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Transient loss of consciousness: The value of the history for distinguishing seizure from syncope (1991)
    Springer
    Journal of neurology 238 (1991), S. 39-43 
    Details
    ISSN: 1432-1459
    Keywords: Seizures ; Epilepsy ; Consciousness disorders ; Medical history taking ; Syncope
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied 94 consecutive patients (age 15 or over) to investigate which aspects of the history and clinical findings help to distinguish seizures from synope and related conditions. Clonic movements or automatism observed by an eyewitness classified an event as a seizure. The seizure group consisted of 41 patients and the syncope group of 53 patients. The likelihood ratio was used to calculate the predictive power of single findings and logistic regression to analyse combinations of findings. The best discriminatory finding was orientation immediately after the event according to the eyewitness and the age of the patient in the absence of an eyewitness report (P〈0.001). We found a seizure five times more likely than syncope if the patient was disoriented after the event and three times more likely if the patient was less than 45 years of age. Nausea or sweating before the event were useful to exclude a seizure. Incontinence and trauma were not discriminative findings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319709
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  • 5
    Electronic Resource
    Electronic Resource
    Clinical evaluation of pneumococcal meningitis in adults over a twelve-year period (1989)
    Springer
    European journal of clinical microbiology & infectious diseases 8 (1989), S. 695-700 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A retrospective study was performed to review the clinical features and outcome of 39 episodes of pneumococcal meningitis in 36 adult patients over a 12-year period. Overall mortality was 33.3%. Only a few of the deaths were directly related to the central nervous system disease and most of them were due to cardiorespiratory failure. Univariate analysis showed that death was more likely to occur in patients with advanced age, an absence of neck stiffness, a high pulse rate, an associated pneumonia, internal complications, or a long duration of the disease (〉7 days) before treatment was started. Patients who died had a higher erythrocyte sedimentation rate and serum bilirubin level and a lower serum sodium level than those who survived. Discriminant analysis showed the development of internal complications to be the strongest predictive factor of a poor outcome of illness. Two other important predictors of a poor outcome were the absence of neck stiffness and associated pneumonia. The history of a skull fracture or head surgery was significantly correlated with a better than average prognosis. The incidence of sequelae in survivors at the time of discharge amounted to 72%. None of the clinical features were significantly correlated with the development of sequelae, except a higher cerebrospinal fluid protein content.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01963754
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    Paper (German National Licenses)
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