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  • 1
    Electronic Resource
    Electronic Resource
    The effect of improvement in diabetic control on plasma and whole blood viscosity (1980)
    Springer
    Diabetologia 19 (1980), S. 345-349 
    Details
    ISSN: 1432-0428
    Keywords: Rheology ; plasma fibrinogen level ; plasma viscosity ; whole blood viscosity ; shear ratek ; Contraves rotational viscometer ; glycosylated haemoglobin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rheological studies were made on the blood of 12 diabetic patients after a period of poor diabetic control (HbA1 12.6±0.7% (mean ± SD); mean home capillary blood glucose level 11.7±1.2 mmol/l), and after at least three months of improved control (HbA1 9.1±0.4%, p〈0.01; mean home capillary blood glucose level 9.2±0.6 mmol/l). There were significant decreases in plasma fibrinogen levels (4.1±0.6 to 3.7±0.6 g/l, p 〈0.01), plasma viscosity (1.31±0.1 to 1.25±0.04, p〈0.001), and whole blood viscosity at low (22.8±2.7 to 20.2±2.9, p〈0.01) and high shear rates (3.4 ±0.2 to 3.1±0.2, p〈0.01). Ten diabetics with clinically evident complications were matched with diabetics of similar age, sex, duration and current control of diabetes. There were no significant differnces in plasma or whole blood viscosities between the two groups. Hyperviscosity in diabetes seems strongly related to hyperglycaemia and to be influenced by the quality of diabetic control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00280518
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The relationship between blood glycosylated haemoglobin and home capillary blood glucose levels in diabetics (1980)
    Springer
    Diabetologia 19 (1980), S. 31-34 
    Details
    ISSN: 1432-0428
    Keywords: Glycosylated haemoglobin ; home blood glucose monitoring ; diabetic control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Serial capillary blood glucose levels from insulin treated patients were recorded over 24 hour periods at fortnightly intervals for three months. Total glycosylated haemoglobin as % of HbA was measured at the end of this period by the Flückiger method, and % HbA1 by column chromatography. There were highly significant correlations between mean blood glucose levels over the three months and % HbA1 (r=0.93, 95% confidence limits 0.84–0.98), and with total glycosylated haemoglobin (r=0.88, 95% confidence limits 0.75–0.94). There was also a good correlation between results obtained by the two methods (r=0.81, p〈0.0001). There were less strong correlations between % HbA1 and blood glucose levels during each of the three months before the estimation, with percentage of glucose levels greater than 10 mmol/l and with mean fasting blood glucose. These data support the hypothesis that % HbA1 and total glycosylated haemoglobin are satisfactory measurements of short term diabetic control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00258307
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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