ISSN:
1434-193X
Schlagwort(e):
Pyrrolidines
;
Piperidines
;
Nitrogen heterocycles
;
Rearrangements
;
Aziridinium
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Treatment of pyrrolidinemethanol derivatives (-)-1, (-)-6, (-)-7, 8, (-)-9, (+)-10, (-)-11, and (-)-21 with trifluoroacetic anhydride and then with Et3N afforded, after hydrolysis of the trifluoroacetyl group with NaOH, the optically active 3-hydroxypiperidines (-)-14, (+)-15, (-)-16, 17, (+)-18, (-)-19, (-)-20, and (+)-22, respectively. The yields are good and the enantiomeric excess excellent (up to 95 %).
Zusätzliches Material:
1 Tab.
Materialart:
Digitale Medien
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