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  • 1
    Electronic Resource
    Electronic Resource
    The changing pattern of paraquat poisoning in man (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 4 (1980), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The clinical and pathological findings are described in 14 patients who died between 6 hours and 26 days after drinking paraquat. Respiratory failure and delayed pulmonary fibrosis have become the hallmark of this poison, but were not the common mode of death in this series. Toxic myocarditis, renal tubular necrosis and centrilobular liver cell damage were significant factors in the eight deaths which occurred within 5 days of paraquat ingestion. Similar abnormalities plus respiratory failure caused the two deaths which occurred 5 and 6 days after consumption of the poison. Respiratory failure was the sole cause of death in only four patients who died 8 to 26 days after drinking paraquat, although the lungs showed pathological changes in all cases. The patients who died in multisystem failure, with one exception, had drunk larger quantities of paraquat than those who survived for a longer period and died in respiratory failure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1980.tb02910.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cerebral damage in paraquat poisoning (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 4 (1980), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This is the first report on cerebral changes in eight patients who died of paraquat poisoning. These included generalized oedema, haemorrhages (both subependymal and subarachnoid), glial reactions (microglial activity and astrocytic response) and meningeal inflammation. Oedema and haemorrhage were the most consistent and significant findings: they suggest that paraquat may damage the cerebral blood vessels. The distribution of haemorrhages was unusual and resembled that seen in thiamine deficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1980.tb02911.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Epithelial tumours of the adult kidney (1999)
    Springer
    Virchows Archiv 434 (1999), S. 281-290 
    Details
    ISSN: 1432-2307
    Keywords: Key words Renal parenchymal carcinoma ; Renal cell carcinoma ; Classification ; Staging ; Grading
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The epithelial tumours of the adult kidney, in particular renal cell carcinoma (RCC), are a variety of neoplasms that can be classified by morphology and genotype. Although most are well characterised, typical and less typical tumour variants are recognised. There is evidence to indicate that stage is one of the most important prognostic factors, irrespective of tumour subtype. However, the appropriate handling of nephrectomy specimens is essential for accurate evaluation of diagnostic and prognostic factors in RCC. The problem of how to achieve more objective nuclear grading is still unresolved. The use of diagnostic decision support systems offers the possibility of a flexible approach to this problem, while still utilising morphological criteria. The histopathological analysis remains important, but new techniques of molecular and cell biology will be providing new tools of extraordinary power to sharpen the diagnosis and give it a biological interpretation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004280050343
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    Paper (German National Licenses)
    Fulltext
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