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  • 1
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  Outlined is our experience with couples in whom the male was both human immunodeficiency virus (HIV) seropositive and a haemophiliac who underwent assisted reproductive technologies (ART) in order to attain family goals while minimizing the risk of HIV transmission. We report their demographics, attitudes towards assisted reproduction, and ART performance and outcomes. The study included HIV serodiscordant couples (n = 11) who underwent ART at a university-based infertility practice from August 1997 to May 2002. Prior to treatment, couples prospectively completed a survey regarding their demographics and attitudes towards assisted reproduction. All couples underwent ART and pregnancy outcomes were analysed. The majority of the patients were fully employed, college-educated, in good health, married and motivated to have a child while minimizing the risk of HIV transmission. Eleven couples underwent 25 cycles of ART [19 in vitro fertilization (IVF) cycles; five frozen embryo transfer cycles; and one oocyte donation cycle] resulting in nine successful pregnancies. The ongoing/delivered pregnancy rate per initiated IVF cycle was 42.1% per embryo transfer. Eight of 11 (72.7%) couples achieved a successful pregnancy. More than half (six of 11; 54.5%) the couples conceived during their initial attempt. Four of nine (44.4%) pregnancies were multiple gestations, including three sets of triplets. All female recipients tested seronegative for HIV at 3 and 6 months post-embryo transfer. All delivered babies (n = 8) tested seronegative for HIV at birth and 3 months postpartum. Four pregnancies are currently ongoing. ART should be considered for HIV serodiscordant couples with haemophilia who desire to have children in order to minimize the risk of viral infection.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-1561
    Keywords: Aggregation pheromone ; Bursaphelenchus cocophilus ; coconut ; Cocos nucifera ; Coleoptera ; Curculionidae ; Dynamis borassi ; 4-methyl-5-nonanol ; palm weevils ; red ring disease ; red ring nematode
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract 4-Methyl-5-nonanol (1) is the male-produced aggregation pheromone of the palm weevil, Dynamis borassi (F.) from Colombia. The pheromone was identified by coupled gas chromatographic–electroantennographic detection (GC-EAD) analysis of male- and female-produced volatiles, and comparative GC–mass spectrometry (MS) of weevil-produced 1. In field experiments in Colombia, traps baited with a stereoisomeric mixture of synthetic 1 (3 mg/day) plus sugarcane captured more weevils than traps baited with 1 or sugarcane alone, suggesting that pheromone and plant volatiles are synergistically attractive. Use of a chiral, stereoisomer-separating Cyclodex-B column in GC-EAD and GC-MS analyses revealed that D. borassi males produce, and antennae of males and females respond to (4S,5S)-1. Previously identified palm weevil (Rhynchophorus spp.) aggregation pheromones 5-methyl-4-octanol (cruentol) and 6-methyl-2-hepten-4-ol (rhynchophorol) also elicited antennal responses by D. borassi. In field experiments, D. borassi females were captured equally well in traps baited with sugarcane plus either 1, cruentol or rhynchophorol. In contrast, D. borassi males were captured most often in traps baited with sugarcane plus 1. Because D. borassi is a potential vector of the red ring nematode that causes the lethal red ring disease of palms, pheromone-based trapping of D. borassi could aid in monitoring or management of red ring disease in commercial palm plantations.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-1561
    Keywords: Coleoptera ; Curculionidae ; Metamasius hemipterus sericeus ; aggregation pheromones ; pheromone chirality ; (4S, 5S)-4-methyl-5-nonanol ; 2-methyl-4-heptanol ; sugarcane ; ethyl acetate ; ethyl propionate ; ethyl butyrate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Coupled gas chromatographic–electroantennographic detection (GC-EAD) analyses and coupled GC-mass spectrometry (MS) of volatiles produced by male and female West Indian sugarcane weevils (WISW), Metamasius hemipterus sericeus (Oliv.), revealed eight male specific, EAD-active compounds: 3-pentanol (1), 2-methyl-4-heptanol (2), 2-methyl-4-octanol (3), 4-methyl-5-nonanol (4), and the corresponding ketones. In field experiments in Florida, alcohols 1–4 in combination with sugarcane were most attractive, whereas addition of the ketones or replacement of alcohols with ketones significantly reduced attraction. In Costa Rica field experiments testing alcohols 1–4 singly and in all binary, ternary, and quaternary combinations revealed 4 in combination with 2 was the major aggregation pheromone, equally attracting male and female WISW. Stereoisomeric 4 and (4S,5S)-4, the only isomer produced by WISW, were equally attractive. Addition of 4S-, 4R- or (±)-2 to (4S,5S)-4 significantly enhanced attraction. Sugarcane stalks in combination with 2 plus 4 (ratio of 1:8) were highly synergistic, whereas EAD-active sugarcane volatiles ethyl acetate, ethyl propionate, or ethyl butyrate only moderately increased attractiveness of the pheromone lure.
    Type of Medium: Electronic Resource
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