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  • 1
    Digitale Medien
    Digitale Medien
    Pathological changes in inbred strains of mice following early thymectomy and irradiation (1981)
    Springer
    Cellular and molecular life sciences 37 (1981), S. 1341-1343 
    Details
    ISSN: 1420-9071
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Mice subjected to thymectomy and irradiation were found to develop a range of pathological change in various organs. These changes were accompanied by antibodies to a variety of self-components. The pattern of pathological and autoimmune change was found to vary with the strain. This strain-related expression did not appear to be associated with the major histocompatibility complex (H-2).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01948400
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  • 2
    Digitale Medien
    Digitale Medien
    A review of major histocompatibility complex-disease associations in man and dog (1987)
    Springer
    Veterinary research communications 11 (1987), S. 119-132 
    Details
    ISSN: 1573-7446
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The organization and biology of the Major Histocompatibility Complexes (MHC) of man (HLA) and dog (DLA) are reviewed, and a summary is presented of laboratory techniques used to define allotypes. The nomenclature of this field and the mechanisms of disease association with the MHC are discussed. Currently recognized HLA-disease associations are enumerated, with emphasis on the value of the complement C4 marker. DLA-disease association studies into autoimmune disease, allergy and neoplasia are reviewed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00344944
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  • 3
    Digitale Medien
    Digitale Medien
    The enhancement of tetrathyridial proliferation ofMesocestoides corti in mice by B.C.G. (1978)
    Springer
    Parasitology research 56 (1978), S. 195-203 
    Details
    ISSN: 1432-1955
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The effects of different doses of B.C.G. given at various periods before infection, on the development of tetrathyridia ofMesocestoides corti was studied. B.C.G. administration was found to exert a complex influence uponM. corti infection in mice. Either enhancement or inhibition of parasite proliferation may occur, depending upon dosage level and the time interval between B.C.G. administration and parasite challenge.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00930750
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  • 4
    Digitale Medien
    Digitale Medien
    The effects of selective immunosuppression on resistance toMesocestoides corti in strains of mice showing high and low initial susceptibility (1983)
    Springer
    Parasitology research 69 (1983), S. 91-104 
    Details
    ISSN: 1432-1955
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Previous work has shown that C57BL/6 mice had the lowest initial susceptibility toMesocestoides corti of six strains of mice examined. Parasite burdens in this strain and in CBA/H mice, a strain showing a higher initial susceptibility toM. corti, were compared following selective immunosuppressive treatments. Irradiation, splenectomy and the administration of cyclophosphamide and methyl prednisolone all resulted in higher parasite burdens in C57BL/6 mice. In contrast these treatments had a minimal effect on parasite burdens in CBA/H mice. In the light of these results the role of antibody in controlling parasite proliferation is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00934013
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  • 5
    Digitale Medien
    Digitale Medien
    The effect of lentinan on the resistance of mice to Mesocestoides corti (1988)
    Springer
    Parasitology research 74 (1988), S. 563-568 
    Details
    ISSN: 1432-1955
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract CBA/H mice were given the immunomodulator lentinan in multipe, ascending doses before (prophylactic) or after (therapeutic) inoculation with tetrathyridia of Mesocestoides corti or as a single prophylactic dose. The latter was without effect, but increasing multiple prophylactic and therapeutic doses of lentinan resulted in a marked reduction in the numbers of parasites in the peritoneal cavity, particularly in those mice that received lentinan therapeutically. In mice that received multiple doses of lentinan, liver granulomas were larger than in controls and there was more collagen deposition and fibrosis. Encapsulated parasites were dead or dying, and such damage appeared to be mediated by increased numbers of macrophages and giant cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00531635
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