ISSN:
1432-2072
Schlagwort(e):
Phencyclindine
;
PCP
;
Pregnancy
;
Teratogenesis
;
Maternal behavior
;
Open field activity
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Abstract Phencyclidine (PCP) (5 mg/kg) was administered daily throughout gestation and pups were cross-fostered or fostered after birth. Prenatal weight gain, length of gestation, length of parturition, and the size and birth weight of the litters were not affected by PCP administration. No congenital malformations were evidence and the mother's health during chronic exposure remained normal. Physical development of the pups (indicated by neonatal weight gain, pinna opening, and eye opening), and neurological development (indicated by the maturity of four reflex actions) were normal for the PCP pups. Behaviorally, PCP pups were slightly more active in the open field at 60 days. Maternal behavior was not influenced by drug treatment, but was affected by the fostering procedures.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00426523
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