ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Push-pull-Butadienes. II. Reactions of 2-Aryl-4,4-bis(methylthio)-1,3-butadiene-1,1-dicarbonitriles with Malononitrile and Ethyl Cyanoacetate2-Aryl-4,4-bis(methylthio)-1,3-butadiene-1,1-dicarbonitriles 1 react with sodium salts of malononitrile or ethyl cyanoacetate 3 to give 4-aryl-2-methylthio-1,4-pentadiene-1,1,5,5-tetracarbonitriles and ethyl-4-aryl-1,5,5-tricyano-2-methylthio-1,4-pentadienecarboxylates 4, respectively. Also, arylethylidenemalononitriles 5 and bis(methylthio)methylenemalononitrile or ethyl bis(methylthio)methylenecyanoacetate 6 afford 4. Substituted dihydropyridines 8 are prepared by treating 4 with aromatic amines. Compounds 4 d, e can be converted to 2-amino-6-aryl-4-methylthio-benzene-1,3-dicarbonitriles 11 a, b.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19813230317
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