ISSN:
0018-019X
Schlagwort(e):
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The results of this study show that three parameters are sufficient to describe the selectivity behaviour of nitrations influenced by mixing as long as a fast combination of the reactant solutions takes place and fast agitation is employed. This is in full agreement with the prediction of the mixing-reaction model developed previously [1]. Furthermore, the results show clearly that in nitromethane the formation rate of nitronium ions from nitric acid is slower than the mixing rate and the rate of the electrophilic substitution proper. From the mixing-disguised selectivity curves for the nitrations of durene and prehnitene with nitronium hexafluorophosphate in nitromethane the ratio of the rate constants k2 for the second nitrations can be estimated to be 1:2. For the two aromatic compounds the k1/k2 ratios are ≥ 104. Finally it could also be shown that small impurities in the solvent (e.g. water) can influence strongly the selectivity curves, depending on the method used for mixing.
Zusätzliches Material:
6 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/hlca.19750580723
Permalink