ISSN:
1432-2277
Keywords:
Key words Malakoplakia
;
Kidney transplantation
;
Immunosuppression
;
Escherichia coli infection
;
Macrophage dysfunction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Malakoplakia is a rare pseudotumoral inflammatory disease known to affect immunocompromised subjects, mainly with a history of recurrent Escherichia coli infection. The urinary tract is the most frequent site of the disease, although all organs can be involved. In the present article, we report a case of malakoplakia of the caecum, that developed in a 52-year-old man, who had received a kidney transplant 9 years before and had a history of recurrent E. coli urinary tract infections. Malakoplakia presented as acute intestinal perforation, and, despite aggressive surgical and medical management, disease progressed toward a fatal outcome due to sepsis and multiple organ failure 9 months later. A defect in the macrophagic activity was demonstrated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s001470050227
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