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  • 1
    Electronic Resource
    Electronic Resource
    Animal experiments (1989)
    [s.l.] : Nature Publishing Group
    Nature 340 (1989), S. 180-180 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Although I am not a neurobiologist and cannot judge critically the significance of the article (Nature 337, 265-267; 1989) referred to by Clive Hollands in his letter (Nature 339, 248; 1989), I am nonetheless as disturbed as he is about the level of suffering involved in the experiments the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/340180a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Timing of the photoperiod and the hour of birth in rats (1976)
    [s.l.] : Nature Publishing Group
    Nature 260 (1976), S. 780-781 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The reproductive functions of the laboratory rat are linked to the diurnal changes in light and darkness. When subjected to an artificial photoperiod with light from 0500 to 1900, rats of most strains release their ovulatory surge of luteinising hormone from about 1500 on the day of prooestrus, and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/260780a0
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  • 3
    Electronic Resource
    Electronic Resource
    Ethical scores for animal experiments (1992)
    [s.l.] : Nature Publishing Group
    Nature 356 (1992), S. 101-102 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] MANY scientists probably occupy the middle ground between the absolutists at either extreme of the animal-rights debate. Neither the abolitionist nor the 'no-restriction' advocate offers a solution to the ethical problem of the use of animals in science that is both practicable and humane. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/356101a0
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  • 4
    Electronic Resource
    Electronic Resource
    Observations on the yolk sac and reichert's membrane of ectopic mouse embryosThis work was supported by United States Public Health grants HD-01050 from the Institute of Child Health and Development and 2-T1-GM-240 from the Institute of General Medical Sciences. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 154 (1966), S. 847-859 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Embryos developing from mouse blastocysts transplanted to the kidneys and testes of recipient mice were studied by light and electron microscopy. The yolk sac and Reichert's membrane of ectopic embryos were morphologically normal and had normal staining and histochemical properties. In electron micrographs Reichert's membrane was of low electron density and had a fine fibrillar structure. The cells of the parietal material within their ergastoplasm that closely resembled the membrane both in texture and electron density. The probability that the parietal yolk sac cells are responsible for the elaboration of Reichert's membrane in the mouse is discussed in relation to other work on the subject.The occurrence of discrete eosinophilic bodies in transplants in which the development of the inner cell mass was abortive is reported. The light microscopic appearance and fine structure of these bodies revealed close similarities to the parietal yolk sac and to Reichert's membrane. It is concluded that they represent yolk sac cells embedded in an abnormal Reichert's membrane.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091540413
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  • 5
    Electronic Resource
    Electronic Resource
    Observations on the development of mouse blastocysts transferred to the testis and kidneyThis work was supported by United States Public Health Grants HD-01050 from the Institutes of Child Health and Development and 2-T1-GM-240 from the Institutes of General Medical Sciences. (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 121 (1967), S. 73-85 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The development of mouse blastocysts transferred to the kidney and testis was studied by light and electron microscopy. Approximately 50% of the blastocysts transferred to both sites survived for more than five days. Although trophoblast proliferation was characteristic of all 31 successful transplants which were serially sectioned, inner cell masses differentiated in only nine. Transplants were invasive in kidney but were encapsulated in testis. In both organs, however, transplants produced considerable hemorrhage. That trophoblast invades by phagocytosis was not substantiated in this study nor was there evidence that trophoblast elaborates a cytolytic factor. Although transplants caused gross lesions in the host organs, the cytology of cells in close proximity to invading trophoblast was almost normal. The only abnormal features observed were the presence of fine fibrillar material in the basal cytoplasm of renal tubule cells and a thickening of their basement membranes. No correlation could be demonstrated between the antigenic dissimilarity of host and transplant and extent of host tissue response.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001210106
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