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  • 1
    Electronic Resource
    Electronic Resource
    Convective mass transfer in large porous biocatalysts: plant organ cultures (1991)
    s.l. : American Chemical Society
    Biotechnology progress 7 (1991), S. 195-199 
    Details
    ISSN: 1520-6033
    Source: ACS Legacy Archives
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bp00008a015
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  • 2
    Electronic Resource
    Electronic Resource
    Large melanoacanthomas: a report of five cases (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 11 (1984), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Five patients with mclanoacanthonia are reported. The skin lesions consisted of a single, round plaque measuring several centimeters in diameter. Histologic findings were characterized by formation within an acanthotic epidermis, of many islands of small basaloid cells and highly dendritic melanocytes. Electron microscopic examination of one lesion revealed a disturbance of melanin transfer from the highly dendritic melanocytes to the neighboring keratinoeytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1984.tb00383.x
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  • 3
    Electronic Resource
    Electronic Resource
    Rippled-pattern trichomatricoma (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 16 (1989), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A hair matrix tumor showing an unusual tumor cell arrangement was found at the base of a solitary trichoepithelioma. Coexisting with solid epithelial islands and immature hair follicle-like structures, areas of alternating epithelial cords and hand-like stroma resembling the Verocay bodies of neurilemmoma or “ripplemarks” on waves were found. In other areas myxomatous degeneration of the stroma changed the rippling into a cribriform pattern. In some parts of the tumor there was a dense melanin pigment associated with MEL5 stained melanocytes. S-100 and GDI (OKT6) antigen stains demonstrated Langerhans cells scattered in the parenchyma and less frequently in the stroma. The majority of tumor cells were considered immature pilar cortical cells because of the following: 1. HKN-6 was strongly positive; 2. a large number of melanocytes were associated with tumor cells in some foci; 3. ultrastructurally immature tumor cells, which had electron-dense tonofilaments and many desmosomes, were transformed without production of trichohyalin granules into semikeratinized cells which showed nuclear degeneration and loss of electron density in tonofilaments. This tumor, however, has not attained the degree of differentiation observed in trichoblastoma (1) another example of an immature cortical cell tumor. Squamous eddy-like or horn pearl-like foci of incomplete keratinization and large keratin-filled cysts were also present within the immature parenchyma, indicating that some immature cells were differentiating toward non-cortical cells, as found in the outer sheath. We would like to designate this tumor “rippled pattern trichomatricoma”, a new entity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1989.tb00004.x
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  • 4
    Electronic Resource
    Electronic Resource
    The Departure of Swallows (1896)
    [s.l.] : Nature Publishing Group
    Nature 55 (1896), S. 6-6 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] I BEG to send you the following extracts from my journal respecting the late appearance of the swallows. 1855, December.-It is worthy of record that several swallows wTere seen in this locality towards the end of November and during the first week of this month. I have ascertained that ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/055006d0
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  • 5
    Electronic Resource
    Electronic Resource
    “Chelidonium majus” as a Cure for Cancer (1896)
    [s.l.] : Nature Publishing Group
    Nature 55 (1896), S. 155-155 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WITH reference to the probable value of Chelidonium majus in the treatment of cancer, I beg to enclose the two following extracts from ancient writers for the purpose of showing that its value, for internal use, was not unknown. In the " Qrtus Sanitatis," of J. A. Cuba, published at ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/055155a0
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  • 6
    Electronic Resource
    Electronic Resource
    Osteopontin adhesion receptors on gingival fibroblasts (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 30 (1995), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Osteopontin (OPN) promotes attachment and spreading of cells in an RGD dependent fashion, suggesting that OPN interacts with integrins on cell surfaces. Here in, we show that LM-609, a monoclonal antibody to the αvβ3 integrin (a vitronectin receptor), inhibited OPN-mediated attachment of gingival fibroblasts. To characterize the cell surface receptors responsible for this interaction, we performed OPN-sepharose affinity chromatography using detergent extracts of 35S-methionine or l25I-surface labeled gingival fibroblasts. Proteins bound to the OPN-matrix were eluted with EDTA and subjected to SDS-PAGE under reducing conditions. EDTA eluates from both 125I-surface labeled and 35Smethionine labeled extracts demonstrated prominent bands in the 90kDa and 50kDa regions, by both autoradiography and fluorography, respectively. These studies suggest that OPN is associated with other cell surface molecules in addition to αvβ3. Furthermore, these as yet to be characterized proteins, may prove to have a stronger affinity for OPN than αvβ3.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1995.tb01250.x
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  • 7
    Electronic Resource
    Electronic Resource
    The Recent Earthquake (1884)
    [s.l.] : Nature Publishing Group
    Nature 30 (1884), S. 57-57 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] I NOTICE that Mr. Topley, at the conclusion of his communication to you respecting the recent earthquake in Essex, remarks, “but at present we know of no observations in the central parts of Kent, Surrey, or Sussex.” I wish therefore to mention, that although I did not myself notice anything in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/030057b0
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  • 8
    Electronic Resource
    Electronic Resource
    Comparison of the electrical properties of neocortical neurones in slices in vitro and in the anaesthetized rat (1988)
    Springer
    Experimental brain research 69 (1988), S. 489-496 
    Details
    ISSN: 1432-1106
    Keywords: Cerebral cortical neurones ; Intracellular recording ; Comparative data from neurones in vivo and in vitro
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Because neurones in isolated brain slices are abnormal in several respects, we have compared the electrical properties of neocortical neurones from the anaesthetized rat with neurones from slices of the same area of neocortex in vitro. Resting potentials were not significantly different but there was a small increase in mean spike amplitude and threshold in slices. The most striking observation was a doubling of the mean apparent input resistance (Rin) of neurones in slices (36 MΩ cf. 18 MΩ in vivo). To assess the extent to which the loss of surface membrane of neurones in slices might contribute to the raised Rin, we estimated the membrane capacity of neurones in the two samples from calculations of the membrane time constants. The mean membrane capacity was significantly lower in neurones from slices, being 2/3 that of the in vivo sample, showing that recordings were indeed mostly from smaller cells in the slices. Possible causes of the difference in mean input resistance not attributable to neuronal size are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00247303
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  • 9
    Electronic Resource
    Electronic Resource
    Cellular response to well-characterized calcium phosphate coatings and titanium surfaces in vitro (1995)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 29 (1995), S. 165-172 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The cellular response to well-characterized Ca-P and Ti surfaces was analyzed. This study indicated that the ion-beam sputtering process could produce a hydroxyapatite-type coating. However, structural alterations such as the incorporation of CO3 and the loss of the OH groups were observed. The Ti surfaces were shown to be predominantly amorphous TiO2. The in vitro cell culture study showed no significant differences in cell number for the Ti and Ca-P surfaces throughout the 12-day study. Furthermore, the initial percentage of protein within the cell layers was significantly lower for cells on Ca-P surfaces compared with the cell layer on Ti surfaces. However, after 3 h incubation, no significant difference in the percentage of protein was observed for the Ti and Ca-P surfaces. © 1995 John Wiley & Sons, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820290205
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