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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 50 (1928), S. 3138-3151 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1041
    Keywords: Key words Antihypertensive treatment ; Hypertension ; Sleep apnea syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: To study the effect of antihypertensive medications on autonomic nervous system in patients with hypertension and sleep apnea syndrome using frequency domain measures of heart rate and blood pressure variabilities. Methods: The β-receptor blocking agent atenolol (50 mg), the calcium antagonist isradipine SRO (2.5 mg), the diuretic hydrochlorothiazide (25 mg) and the ACE inhibitor spirapril (6 mg) once daily were given in a double-blind crossover schedule for 8 weeks. Cardiovascular autonomic control was assessed using frequency domain measures of heart rate variability during the spontaneous and controlled breathing tests. During orthostatic maneuver and cold pressor test the blood pressure variability analysis also was performed. Results: In general, the responses of heart rate and blood pressure variabilities were abnormal in the patients with arterial hypertension and sleep apnea syndrome compared to reference data. Of the four drugs, only atenolol effected heart rate and blood pressure variabilities as it shifted the autonomic regulation to the vagal direction. Other antihypertensive drugs did not change any parameter of heart rate or blood pressure variabilities. Conclusion: The short-term treatment with atenolol in patients with arterial hypertension and sleep apnea syndrome is associated with normalization of autonomic nervous control judged by heart rate and blood pressure variability. Thus, β-receptor blockade may have adjunctive beneficial effects beyond blood pressure reduction in these patients. However, the long-term effects of blood pressure reduction on autonomic nervous control remain to be studied.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 4 (1933), S. 99-122 
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Clinical autonomic research 3 (1993), S. 183-187 
    ISSN: 1619-1560
    Keywords: Cardiac dysrhythmias ; cardiovascular reflext tests ; autonomic ; myocardial infarction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To assess the possible dysrhythmogenic effect of cardiovascular autonomic function tests, ECG tracings of 925 consecutive subjects, taken during a battery of cardiovascular autonomic reflex tests were analyzed. The battery included the Valsalva manoeuvre, deep breathing test, orthostatic and isometric handgrip. The frequency of ventricular extrasystoles increased during or after the tests, compared with the resting phase, in 11% of healthy subjects, in 11% of diabetic subjects and in 23% of subjects with a previous myocardial infarction (p = 0.001vs healthy subjects). In patients with previous myocardial infarction, the most dysrhythmogenic individual tests were orthostatic and isometric handgrip. In nine subjects, other cardiac rhythm disturbances were detected (including nonsustained ventricular tachycardia, conduction block, and atrial fibrillation). In all cases, the dysrhythmias were asymptomatic and resolved without medical intervention. In conclusion, we consider the cardiovascular reflex test battery safe for the patient. However, due to occasional potentially significant dysrhythmias we recommend continuous monitoring of the electrocardiogram and immediate access to resuscitation facilities during cardiovascular autonomic testing.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 74 (1928), S. 135-137 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Clinical rheumatology 2 (1983), S. 251-257 
    ISSN: 1434-9949
    Keywords: kw]Ankylosing Spondylitis ; Spinal Flexion Mobility ; Muscle Function Tests
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The comparative results of four tests (a dynamometer, a single and a repetitive dynamic and a static test) to determine the performance capacity of trunk muscles in ankylosing spondylitis are reported. Seventeen men and four women, aged 31 to 35 yrs, were examined. Trunk muscle performance was compared with the flexion mobility of the spine and ESR. The best correlation between muscle capacity of trunk extensors and spinal mobility was seen in the static trunk extensor test. The best correlation between muscle capacity of trunk flexors and spinal mobility was seen in the single dynamic test. Because the comprehensive exercise therapy including muscle strengthening is supported by our results and there is no generally recommended test for evaluating the performance capacity of trunk muscles, it seems reasonable to develop such tests of trunk muscles for clinical assessment of ankylosing spondylitis. Clinical trials to ensure the positive effect of welltrained trunk muscles in ankylosing spondylitis are still lacking.
    Type of Medium: Electronic Resource
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