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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 2838-2846 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The first radial mode of a cylindrical resonator was excited in extracavity and intracavity configurations employing a modulated 3.39 μm HeNe laser. The resonance curves were measured as a function of pressure by a computer-controlled method and fitted to Lorentzian profiles. Measurements were performed for C2H4, CH3Cl, CH3F, C2H6, and CH4, where the optical absorption coefficient determined by transmission experiments increases from C2 H4 to CH4 . From the signal strengths and the Q factors of the resonances the so-called photoacoustic signal (PAS) was determined and compared with theory. Good agreement between theory and experiment was observed for all extracavity measurements and in the case of intracavity experiments with low optical losses in the laser resonator. In order to describe the large discrepancies between the experimentally determined PAS and the existing theory for high losses, improved models were developed, which are based on an inhomogeneous distribution of laser power in the optical cavity. Deviations from these models were found near threshold. The PAS observed above threshold is attributed to amplified spontaneous emission.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: substantia nigra ; tolbutamide ; dopamine ; GABA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A high density of binding sites for sulphonylureas is found in the substantia nigra. These binding sites may be linked to ATP-regulated K-channels (K-ATP channels) as sulphonylureas selectively inhibit these channels in pancreatic ß-cells. We have studied the effect of the sulphonylurea tolbutamide on the electrical properties of freshly isolated neurones from guinea-pig substantia nigra, using the perforated patch technique. In spontaneously firing cells, both the D2 agonist quinpirole and the GABAB agonist baclofen abolished firing, hyperpolarised the cell and increased the whole-cell conductance. Tolbutamide reversed all three effects, but was without effect in the absence of quinpirole or baclofen. We suggest that D2 and GABAB receptors activate a K-channel that is blocked by tolbutamide.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 43 (1987), S. 57-59 
    ISSN: 1432-0649
    Keywords: 07.62.+S ; 42.60.DA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Intracavity and extracavity photoacoustic resonance experiments have been performed for C2H4, using a cylindrical acoustic resonator and a 3.39 μm HeNe laser as a light source. The pressure dependence of the photoacoustic signal of the first radial mode excited in the acoustic resonator was studied as a function of C2H4 pressure. It is shown that theory yields a reasonable description of the experimental results taking into account the effective laser power.
    Type of Medium: Electronic Resource
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