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  • 1
    Electronic Resource
    Electronic Resource
    Cytokines in NZB CD5+ B Clones (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 651 (1992), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1992.tb24668.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Tachykinins can partly explain the link within the neuroendocrine-immune-hematopoietic axis: novel role for mesenchymal stem cells (2004)
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Experimental dermatology 13 (2004), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The tachykinins are among major regulators of bone marrow (BM) functions. The BM is resident to two stem cells: hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). The adult BM has a finite number of HSCs that are required to replenish the immune system throughout life. MSCs surround BM vasculature, while HSCs are located close to the endosteal regions. The mechanisms by which the tachykinins regulate hematopoiesis require further research. Innervated fibers in the BM form synapse-like structures with MSCs. We propose that tachykinin-mediated effects on MSCs are relevant to hematopoiesis, because MSCs: 1) generate hematopoietic supporting stromal cells, 2) regulate the movement of cells in and out of the BM, and 3) regulate inflammatory responses in the BM. This study focuses on the truncated tachykinin receptor (NK-1-Tr). Its expression and regulation on MSCs mirrors the brain, but contrasts BM stroma. NK-1-Tr is predominantly expressed on MSCs. Because of limited receptor desensitization, we propose that NK-1-Tr on MSCs could allow rapid responses to the tachykinins so as to maintain the vascular/barrier functions of the BM, regulate immune responses to infectious agents that could be threat to BM failure, and respond to rapid loss of blood. Part of the mechanisms by which the tachykinins regulate MSCs functions involve novel interactions between IFN-γ and MHC class II. The findings described in this study hold clues to the role of tachykinins on hematopoiesis and adult stem cell functions in the BM. This report adds to an understanding of the crosstalk within the neural-immune-hematopoietic axis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0906-6705.2004.00212c.x
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  • 3
    Electronic Resource
    Electronic Resource
    Why is the central gas disk of the Galaxy tilted? (1981)
    [s.l.] : Nature Publishing Group
    Nature 290 (1981), S. 120-121 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The original motivation for the theory4-7 was to provide an explanation for the warps in the outer parts of spiral galaxies, and it has satisfactorily explained several observations8. The model shows that the warp arises as a self-excited bending wave which is driven unstable because of its motion ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/290120a0
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  • 4
    Electronic Resource
    Electronic Resource
    Insect-resistant transgenic brinjal plants (1998)
    Springer
    Molecular breeding 4 (1998), S. 33-37 
    Details
    ISSN: 1572-9788
    Keywords: Bacillus thuringiensis ; insecticidal crystal protein gene ; cry1Ab ; brinjal ; fruit borer ; Leucinodes orbonalis ; transgenic plants
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract A synthetic cry1Ab gene coding for an insecticidal crystal protein (ICP) of Bacillus thuringiensis (Bt) was transferred to brinjal (eggplant) by cocultivating cotyledonary explants with Agrobacterium tumefaciens. Transformant plants resistant to kanamycin were regenerated. Hybridization experiments demonstrated gene integration and mRNA expression. Double-antibody sandwich ELISA analysis revealed Bt toxin protein expression in the transgenic plants. The expression resulted in a significant insecticidal activity of transgenic brinjal fruits against the larvae of fruit borer (Leucinodes orbonalis). The results also demonstrated that a synthetic gene based on monocot codon usage can be expressed in dicotyledonous plants for insect control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009694016179
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  • 5
    Electronic Resource
    Electronic Resource
    A methodology for screening hydrocracking catalysts (1995)
    Chichester : Wiley-Blackwell
    Journal of Chemical Technology AND Biotechnology 64 (1995), S. 195-199 
    Details
    ISSN: 0268-2575
    Keywords: Hydrocracking ; bifunctional catalyst ; hydrogenation/cracking activity ; hydroisomerization ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Hydroconversion of n-heptane and toluene has been studied over a commercially proven Ni-W/SiO2-Al2O3 amorphous base hydrocracking catalyst (suitable for maximizing middle distillates production from heavier feedstocks) under a wide range of operating conditions (pressure: 400-1200 psig; temperature: 315-360°C, liquid hourly space velocity (LHSV) ≃ 1 h-1 and molar hydrogen/hydrocarbon feed ratio: 6-8) to assess the hydrogenation and cracking activities of the catalyst screening. Hydroisomerization followed by hydrocracking, ad hydrogenation followed by isomerization have been found to be the major reaction with n-heptane and toluene respectively as the feeds. The hydroconversion of toluene gives a very high selectivity of hydrogenated product. With n-heptane, a very high selectivity of hydroisomerized product, together with a high ratio of hydroisomerized to hydrocracked product, is obtained.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jctb.280640213
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    Paper (German National Licenses)
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