ISSN:
0392-6737
Keywords:
Physics of bioenergetic processes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Physics
Notes:
Summary In the present study of fusion between lipid vesicles performed by thermomechanical analysis, isothermal volume variation has been shown to be a reliable tool to follow these kinetics without introducing perturbing probes. In fact, the fusion process is accompanied by bilayer strain release which causes an overall volume decrease of the fused vesicles. Volumetric variations induced by side processes, such as adhesion or ion binding onto the vesicle surface, were accounted for in our measurements. Moreover, by the same technique we followed segregation effects of the membrane lipid components in mixed vesicles. The systems examined were neutral and anionic phospholipids containing vesicles. The role of temperature, vesicle size, lipid composition as well as the influence of different cations were also investigated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02457289
Permalink