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Conformational differences in bacterial ribosomal RNAs in non-denaturing conditions (1976)

REFF, M. E. ; STANBRIDGE, E. J.

[s.l.] : Nature Publishing Group

Nature 260 (1976), S. 724-726

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] The relevant bacterial species were labelled with 3H-5-uridine or 14C-2-uridine and the rRNA was extracted and electrophoresed in composite polyacrylamide?Agarose gels as described in the legend to Fig. 1. Figure 1a shows the clear separation of both 23S and 16S peaks of the rRNAs from S.faecalis ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/260724a0

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Cell culture aging (1981)

Reff, M. ; Schneider, E. L.

Springer

Molecular and cellular biochemistry 36 (1981), S. 169-176

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ISSN: 1573-4919

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology , Medicine

Notes: Summary Cellular research in aging has been stimulated by the observation that human diploid cells have a limited number of cell divisions in culture. This loss of cellular proliferation (in vitro senescence) has been extensively studied by biochemical, clonal, and genetic analysis. Studies of human skin fibroblast cultures have revealed thatin vitro senescense is related toin vivo human cellular aging. Recently differentiated cells have been proposed for aging studies. These cells may provide additional information on aging since alterations ofin vitro cellular functions may be related to thein vivo behavior of specific differented cell types.