ISSN:
1432-0428
Keywords:
Aortic endothelium
;
alloxan diabetes
;
scanning electron microscopy
;
atherosclerosis
;
argyrophilic cells
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Scanning electron microscope studies of the aorta and other major arteries have been performed in alloxan-induced diabetic rabbits. After 5 weeks, a variety of structural abnormalities of the endothelial lining were detected including a significant increase in the number of argyrophilic cells and an increased number of craters or openings in the endothelial junctional region. Evidence of more extensive micro-damage was present after 5 months duration of diabetes. These zones with structural changes in the endothelial lining of major vessels seem to be areas of high predilection to atherosclerosis in diabetes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00253578
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