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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 35 (1913), S. 754-759 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 33 (1911), S. 1363-1365 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of food science & technology 1 (1966), S. 0 
    ISSN: 1365-2621
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary. The ability of unripe bananas to synthesize ethylene is dependent on the oxygen tension of the atmosphere surrounding the fruit. Unripe bananas do not synthesize significant amounts of ethylene at 18°C unless the oxygen tension is above 7–8.0%. At oxygen tensions of 10–13% synthesis does occur but it is delayed compared with fruit in the air. It has been demonstrated that delay in the onset of the ripening syndrome occasioned by holding fruit in 5–7.5% oxygen is caused by their inability to synthesize ethylene. The ripening syndrome may, however, be initiated even in atmospheres of low oxygen by the inclusion of exogenous ethylene in physiological concentrations. Once the synthesis is initiated, the fruit are capable of producing ethylene even in atmospheres of low oxygen.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Elevated oestradiol concentrations during the follicular phase stimulate a surge in gonadotropin-releasing hormone (GnRH) and luteinising hormone (LH) concentrations, which leads to ovulation. Progesterone can block the oestradiol-induced GnRH/LH surge, but the mechanism that is involved is unclear. We examined the effect of progesterone on oestradiol-induced activation of cells within the ovine hypothalamus/preoptic area (POA) to determine: (i) in which regions progesterone acts to block the GnRH/LH surge and (ii) whether progesterone directly or indirectly prevents activation of oestradiol-responsive cells. Cellular activation was assessed by measuring the number of cells that expressed Fos (an immediate early gene). Exposure to increased oestradiol concentrations in the absence of progesterone (which normally stimulates a LH surge) did not cause any region-specific changes in hypothalamic Fos expression during the activation stage of the LH surge-induction process (Experiment 1). The same treatment significantly increased cellular activation within the POA, lateral septum (LS), and arcuate nucleus at the time of surge onset (Experiment 2). Concurrent exposure to increased oestradiol and progesterone concentrations during the activation stage of the surge-induction process (which normally blocks the LH surge) was associated with significantly reduced cellular activation within the ventromedial hypothalamus and anterior hypothalamic area, relative to the positive controls (oestradiol increment alone) and arcuate nucleus relative to the negative controls (no increment in oestradiol) during the activation stage (Experiment 1). At the time of surge onset (Experiment 2), exposure to progesterone during the activation period prevented the oestradiol-induced increase in cellular activation that occurred in the POA, LS and arcuate nucleus of the positive controls. These results demonstrated that oestradiol and progesterone induced differential region- and time-specific effects on cellular activation within the regions of the ovine brain that generate the preovulatory GnRH/LH surge. Moreover, the lack of cellular activation within the POA, LS and arcuate nucleus at the time of surge onset in animals exposed to progesterone during the activation stage is consistent with the hypothesis that progesterone can block the preovulatory surge by direct inhibition of oestradiol-induced cellular activation in these areas.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Progesterone is the ovarian hormone that times events in the ovine reproductive cycle. When elevated, this ovarian hormone acts centrally to inhibit both the tonic and surge modes of gonadotrophin releasing hormone (GnRH) release. Two studies were performed to address the underlying neural mechanisms. The first tested the hypothesis that the rapid rise in GnRH release, that results from an acute fall in progesterone concentrations (such as occurs following luteolysis), is temporally associated with a rapid rise in the cellular content of GnRH mRNA. Three groups of ovariectomised (OVX) ewes were treated with exogenous progesterone for 10 days, while one remained steroid free (OVX, n=7). To determine the effects of acute progesterone (P) withdrawal, ewes were killed on day 10 while implants were still in place (OVX+P, n=6) or 4 (OVX-P4, n=7) or 12 h (OVX-P12, n=7) after progesterone removal. Coronal sections through the rostral portion of the medial preoptic area (rPOA) were processed for cellular in-situ hybridization for GnRH mRNA. An increase in progesterone concentrations markedly suppressed luteinizing hormone (LH) release, while removal of the implants caused progesterone concentrations to fall (P〈0.01) within 1 h and LH pulse frequency to increase (P〈0.05) within 4 h. Despite these progesterone-induced changes in LH/GnRH release there were no differences in the cellular content of GnRH mRNA among the four groups. In the second study, three groups of ovariectomised ewes were used to determined whether the inhibitory actions of early (EL; n=8) and mid-luteal (ML; n=8) phase concentrations of progesterone on LH release are accompanied by a decrease in GnRH mRNA expression. P inhibited the secretion of LH in a dose dependant manner; pulses of LH were virtually absent in the ML group. Despite this marked inhibitory steroid action, there was no significant difference in the cellular content of GnRH mRNA among the OVX, OVX (EL) and OVX (ML) groups. Thus, both the negative feedback actions of physiological concentrations of progesterone on GnRH release and the rapid escape from progesterone-inhibition are independent of changes in the cellular content of GnRH mRNA. These data suggest that the mechanism by which progesterone controls the timing of events in the ovine oestrous cycle is primarily by altering the secretion of GnRH rather than GnRH biosynthesis.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Our data, COllected as part of the joint global ocean flux (JGOFS) bloom study, COnsist of high-precision surface PC02 and TIC measured simultaneously and COntinuously, together with a COmprehensive description of hydrographic and biologi-cal COnditions from the surface down to a depth of 300m, ...
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1 Mammal faunas of the Marsworth channels Upper channel Elephant (indeterminate) Dicerorhinus hemitoechus (Falconer) Hippopotamus amphibius LinnMegaceros giganteus (Blumenbach) Cervus elaphus LinnBison priscus Bojanus Arvicola terrestris LinnMicrotus sp. Lower channel Canis lupus ...
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The role of urinary toxins in interstitial cystitis (IC) has been suggested. This report describes the partial purification of a substance from human urine that inhibited in vitro colony formation by mouse fibroblasts. Urine samples from 15 women with IC and 17 healthy women serving as volunteers were fractioned by ultrafiltration and chromatography methods and tested by the inhibition of Swiss 3T3 fibroblast colony formation. The fibroblasts were cultured at low density with varying concentrations of whole or fractioned urine. Colonies were counted at 10 days. Colony formation was reduced by incubation with whole urine, ultrafiltrate, and nonadsorbed C18 fractions. Inhibition of colony formation by urine from healthy volunteers or women with IC was not significantly different. In vitro colony formation by Swiss 3T3 cells was inhibited by a component of human urine. The toxicity of urine from IC patients was not different from that of urine from healthy controls.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 12 (1977), S. 919-926 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A study is presented of the stress inside a two-dimensional elastic solid which has a boundary surface angle and which is loaded by an internal point source of expansion. An exact analytic solution for the stress is obtained, for general surface angle and source position, and evaluated numerically for several representative cases of wedges and notches. The singular behaviour given by the leading terms near the angle vertex is found to be highly localized, and there is little or no stress enhancement near the source. For many combinations of boundary angle and source location, however, a local region of significant enhancement occurs on that part of the surface nearest the source. Implications of these results are discussed, with particular reference to surface steps.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Mathematical geology 3 (1971), S. 327-328 
    ISSN: 1573-8868
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Type of Medium: Electronic Resource
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