ISSN:
1432-0703
Source:
Springer Online Journal Archives 1860-2000
Topics:
Energy, Environment Protection, Nuclear Power Engineering
,
Medicine
Notes:
Abstract Gas chromatographic methods are described for the trace analysis of 3,3′-dichlorobenzidine and its dihydrochloride salt in animal chow, wastewater, and human urine. Salient elements of the method for these known carcinogens in chow are: Extraction of the residues as the free amine and a cleanupvia acid-base liquid-liquid partitioning with benzene followed by a silica gel column. With wastewater and human urine, residues are adsorbed by percolating the sample through a column of XAD-2, eluted with acetone, and cleaned up with acid-base partitioning and a silica gel column. Residues are assayed by gas chromatography (GC) either as the free amine or after conversion to the pentafluoropropionyl (PFP) derivative by using an electron capture (EC) or a rubidium-sensitized thermionic-type (N/P) detector. Minimum detectable residues in chow, wastewater, and human urine are about 3 ppb, 18 ppt and 60 ppt, respectively, as determined by EC-GC of the PFP derivative.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02097786
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