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  • 1
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für Lebensmittel-Untersuchung und -Forschung 207 (1998), S. 249-252 
    ISSN: 1431-4630
    Keywords: Key words Tomato ; Pectinmethylesterase ; Polygalacturonase ; Manothermosonication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract  The resistance of tomato pectic enzymes to manothermosonication (MTS), a combined treatment of heat and ultrasound under moderate pressure, was studied. Pectinmethylesterase (PMF) and polygalacturonases (PG) I and II were inactivated much more efficiently by MTS than by simple heating. In MTS inactivation of these enzymes, the effect of heat and ultrasonic waves was synergistic. D values [the time required for the (original) enzyme activity to decrease by 90%] for PME heat inactivation at 62.5  °C were reduced 52.9-fold by MTS and those for PG I at 86  °C and PG II at 52.5  °C, 85.8-fold and 26.3-fold, respectively.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 189 (1994), S. 531-537 
    ISSN: 1432-0568
    Keywords: Embryonic chick gonad ; Sertoli cell ; Differentiation ; In vitro feminization ; Sex-specific antigen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Male and female gonads from 7- to 9-day-old chick embryos were cultured for 6 days in Sertoli cell-conditioned medium or in serum-free medium to investigate the possible effect of substances secreted by rat Sertoli cells on chick gonad development. Histological analysis showed that whereas all female gonads proceed through normal ovarian development in both culture media, most of male gonads showed clear feminization only when cultured in Sertoli cell-conditioned medium; male gonads cultured in serum-free medium developed as normal testes. Because the only substance detected in our conditioned medium with the potential to cause these effects was sex-specific antigen (Sxs), our results provide further evidence that Sxs antigen may play a role in sexual differentiation in birds, and probably in mammals.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 25 (2000), S. 490-496 
    ISSN: 1432-0509
    Keywords: Key words: Liver, neoplasms—Liver, CT—Computed tomography (CT) helical.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: The purpose of our study was to evaluate the imaging features and patterns of contrast enhancement in peripheral cholangiocarcinomas with computed tomography (CT) and correlate these features with histologic findings when available. Methods: We reviewed the CT scans of 24 patients with 25 peripheral cholangiocarcinomas proved by orthotopic liver transplantation (n= 1), liver resection (n= 7), percutaneous needle biopsy (n= 10), and fine needle aspiration biopsy (n= 6). Incremental dynamic nonhelical CT was performed in four cases and helical CT in 21 cases. Portal venous phase images were obtained in all 25 cases. Fourteen patients underwent helical CT during arterial and portal phases. Delayed images were obtained in 20 patients. Results: The size of the tumors ranged from 1.2 to 17 cm. Bile duct dilatation was present in 13 patients (52%), and regional lymph node enlargement was observed in six patients (24%). Retraction of the liver capsule was present in nine patients (36%). In eight patients (32%), satellite nodules were also detected. All tumors were globally hypodense during the portal phase. In 14 patients (70%), delayed images disclosed hyperattenuating tumors. Rimlike contrast enhancement was the most frequent pattern observed in either arterial (57% of patients) or portal (60% of patients) phase imaging. Portal venous encasement was seen in 10 patients (40%). Conclusion: In the proper clinical setting, detection of a hypodense hepatic lesion with peripheral enhancement, biliary dilatation, and contrast enhancement on delayed images are highly suggestive of peripheral intrahepatic cholangiocarcinoma.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Resumen (translated by E. Pascual) Durante la década pasada, la Faja Pirítica Ibérica (FPI) ha sido un área de actividad minera e investigación cientifica renovadas, lo que ha conducido a la obtención de nuevos datos y conceptos geológicos y metalogénicos, que se exponen sucintamente en este Número Especial. La razón de este interés en la FPI, que forma parte del cinturón orogénico hercínico, es que sus rocas, cuyas edades abarcan desde el Devónico tardío al Carbonífero Medio, albergan una enorme cantidad de mineralizaciones de sulfuros masivos ligados a vulcanismo (1700 millones de toneladas de sulfuros, que totalizan 14,6 Mt de Cu, 13,0 Mt de Pb, 34,9 Mt de Zn, 46100 toneladas de Ag y 880 toneladas de Au). Las mineralizaciones y su entorno muestran signaturas que se pueden relacionar con la mineralogía y la zonación de las masas de sulfuros, con los isótopos de plomo de la mineralización, con las variaciones en los halos de alteración hidrotermal alrededor de las mineralizaciones, con los caracteres geoquímicos de las rocas volcánicas bimodales que albergan los sulfuros masivos, con la compleja evolución tectónica del conjunto durante la orogenia hercínica, con la existencia de paleofallas y estructuras sinsedimentarias que actuaron como canales y trampas de descarga para los fluidos metalíferos y los gossans que se desarrollaron sobre los sulfuros. Se han deducido criterios geológicos discriminantes para cada área de conocimiento, que pueden ser útiles para la exploración minera, complementando las técnicas más tradicionales de prospección. Aunque la cuestión del entorno geodinámico de la FPI todavía es materia de debate, cualquier interpretación tiene que tener ahora en cuenta algunas restricciones incontrovertibles: por ejemplo, los caracteres geoquímicos de una gran parte de las rocas básicas son comparables a los de basaltos derivados del manto y emplazados en entornos tectónicos extensionales, y las rocas ácidas asociadas se produjeron a partir de un protolito cortical básico, a presiones bajas o intermedias y asociadas a un abrupto gradiente térmico. Por consiguiente, la secuencia vulcanosedimentaria que contiene los sulfuros masivos difiere claramente de las series recientes relacionadas con entornos de arco. Consideramos aquí que el entorno tectónico fue extensional y epicontinental y que tuvo lugar durante la convergencia de placas hercínica, que culminó en deformación “thin-skinned” y acreción del terreno constituído por la Zona Sudportuguesa al bloque continental paleozoico ibérico.
    Notes: Abstract The Iberian Pyrite Belt (IPB) has, over the past decade, been an area of renewed mining activity and scientific research that has resulted in a wealth of new data and new geological and metallogenic concepts that are succinctly presented in this Thematic Issue. The reason for this interest in the IPB, which forms part of the Hercynian orogenic belt, is that its Late Devonian to Middle Carboniferous rocks host a huge quantity of volcanic-hosted massive sulphide (VMS) mineralization (1700 Mt of sulphides, totalling 14.6 Mt Cu, 13.0 Mt Pb, 34.9 Mt Zn, 46100 t Ag and 880 t Au). The mineralization and its environment display a number of typical signatures that can be related to the mineralogy and zoning of the sulphide orebodies, to the lead isotopes of the mineralization, to the geochemical and mineralogical variations in the hydrothermal alteration halos surrounding the orebodies, to the geochemical characteristics of the bimodal volcanics hosting the VMS, to the complex structural evolution during the Hercynian orogeny, to the presence of palaeofaults and synsedimentary structures that acted as channels and discharge traps for the metalliferous fluids, and to the gossans developed over VMS. Discriminant geological criteria have been deduced for each domain which can be helpful in mineral exploration, complementing the more traditional prospecting techniques. Although the question of the IPB's geodynamic setting is still under debate, any interpretation must now take into account some incontrovertible constraints: for example, the geochemical characteristics of a large part of the basic lavas are comparable to those of mantle-derived basalts emplaced in extensional tectonic settings, and the associated acidic rocks were produced by melting of a basic crustal protolith at low- to medium-pressures and a steep geothermal gradient, thus, the sulphide-bearing volcano-sedimentary sequence differs strongly from recent arc-related series. It is considered here that the tectonic setting was extensional and epicontinental and that it developed during the Hercynian plate convergence, that culminated in thin-skinned deformation and accretion of the South Portuguese terrane to the Iberian Paleozoic continental block.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusions In group A there was a fall in PVRI while SVRI was maintained stable, both of them were statistically significant (#). Urine output, FENa and FECl were slightly higher in group A, but none of these were statistically significant (*).
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The fragile X mental retardation syndrome is caused by an expansion of a trinucleotide repeat (CGG)n in the FMR-1 gene. Molecular genetic study of fragile X provides accurate diagnosis and facilitates genetic counseling in families with affected members. We present here the molecular study of 59 Spanish fragile X syndrome families using probe StB 12.3 and the polymerase chain reaction (PCR) of the (CGG)n repeat sequence of the FMR-1 gene. The results obtained have allowed us to characterize 455 individuals, including eight prenatal diagnoses. The clinical diagnosis of fragile X in 89 affected males was confirmed, 137 female carriers were identified (48 of whom were mentally retarded), 176 individuals “at risk” were found not to have the expansion, and 12 cases of normal transmitting males (NTM) were detected. In the sample studied, no de novo mutations were detected, nor any mutation different from that described for the (CGG)n expansion. One nonmentally retarded male was detected as having an unmethylated CpG island for the FMR-1 gene, but with more than 200 CGG repeats (high functioning male). The analysis of the (CGG)n repeat in 208 normal chromosomes gave an allele distribution similar to that in other Caucasoid population groups, with alleles of 29 and 30 CGG repeats accounting for 46% of the chromosomes. The combination of Southern analysis and PCR of the (CGG)n repeat is highly efficient for diagnosis, compared with cytogenetic techniques, especially in the detection of female carriers, NTMs, and prenatal diagnosis, enabling accurate genetic counseling to be provided in all cases.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 6 (1996), S. 448-450 
    ISSN: 1432-1084
    Keywords: Giant hemangioma ; Cavernous hemangioma ; Liver neoplasms ; CT ; MR
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The CT and MR appearance of giant cavernous hemangiomas can be confusing, and some atypical radiographic findings have been described. We report the CT and MR features of a giant cavernous hemangioma of the liver with atypical presentation. CT showed a large hypodense geographical lesion involving the majority of the liver and multiple scattered peripheral lesions. The T2-weighted MR images revealed a huge hyperintense lesion with multiple satellite nodules.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0945-3245
    Keywords: AMS(MOS): 65N30 ; CR: G18
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Description / Table of Contents: Summary Explicit bounds for the best polynomial approximation error, explicit and non-explicit bounds for the Lagrange interpolation error are derived for functions belonging to fractional order Sobolev spaces defined over a bounded open set in ℝ n . Thus the classical results of the integer order Sobolev spaces are extended.
    Notes: Résumé On établit des majorations explicites de I'erreur de meilleure approximation polynomiale ainsi que des majorations explicites et nonexplicites de I'erreur d'interpolation de Lagrange, lorsque la fonction considérée appartient à un espace de Sobolev d'ordre non entier défini sur un ouvert borné de ℝ n . Les résultats obtenus généralisent les résultats connus dans le cas des espaces de Sobolev d'ordre entier.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 85 (1986), S. 5128-5131 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The nonrelativistic anharmonic–asymmetrical–oscillator (AAO) is studied in full. The classical equation of motion is solved using Jacobi elliptic functions which have both real and imaginary periods. The imaginary period is connected with the imaginary part of the energy in quantum mechanics. The resonances (Siegert states) are calculated in the JWKB approximation.
    Type of Medium: Electronic Resource
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