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  • 1
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Components of heart rate variability have attracted considerable attention in psychology and medicine and have become important dependent measures in psychophysiology and behavioral medicine. Quantification and interpretation of heart rate variability, however, remain complex issues and are fraught with pitfalls. The present report (a) examines the physiological origins and mechanisms of heart rate variability, (b) considers quantitative approaches to measurement, and (c) highlights important caveats in the interpretation of heart rate variability. Summary guidelines for research in this area are outlined, and suggestions and prospects for future developments are considered.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 32 (1995), S. 0 
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: The purpose of this paper is to analytically evaluate and compare two of the most common methods for measuring respiration-related heart rate fluctuations: linear detrended heart rate power spectral analysis and the Porges technique of filtered variance. Low-frequency power was removed from instantaneous 4-Hz R-R interval signals using either a first-order linear (linear/spectral technique) or a third-order polynomial (MPF-var technique). The signals were band-pass filtered and analyzed in both the time and frequency domains. Although in most cases the two techniques yielded substantially similar results, the MPF-var technique resulted in signal amplification at a few specific frequencies. The frequency range and effect of amplification of the MPF-var technique were dependent upon the polynomial size, sampling frequency, and frequency content of the signal.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 6 (1995), S. 0 
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Arrhythmias in Children. In recent years, the distinction between the diagnostic and therapeutic techniques used in the assessment and management of pediatric and adult patients with arrhythmias has gradually blurred. Nonetheless, arrhythmias in the pediatric patient are still often different from the adult patient in one of two important ways. First, a variety of arrhythmia mechanisms remain relatively unique to the pediatric population, some because of developmental issues and others because of early presentation of an incessant tachycardia. Second, the presentation and management of certain arrhythmias is sometimes markedly affected by patient age or the presence of structural congenital heart disease. A sampling from each of the above categories is reviewed and discussed.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Between May 1990 and March 1995, 5 of 29 young patients (ages 4.2–25 years; median 14.1 years) undergoing RF ablation for atrioventricular node reentrant tachycardia (AVNRT) presented with spontaneous accelerated junctional rhythm (AJR) (CL = 500–750 ms), compared to 0 of 58 age matched controls undergoing RF ablation for a concealed AV accessory pathway (P = 0.004). In 3 of the 5 patients with AVNRT and AJR, junctional beats served as a trigger for reentry. During attempted slow pathway modification in the five patients with AVNRT and AJR, AVNRT continued to be inducible until the AJR was entirely eliminated or dramatically slowed. These 5 patients are tachycardia-free in followup (median 15 months; range 6–31 months) with only 1 of the 5 patients continuing to experience episodic AJR at rates slower than observed preablation. Episodic spontaneous AJR is statistically associated with AVNRT in young patients and can serve as a trigger for reentry. Successful modification of slow pathway conduction may be predicted by the elimination of AJR or its modulation to slower rates, suggesting that the rhythm is secondary to enhanced automaticity arising near or within the slow pathway.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    350 Main Street , Malden , MA 02148-5018 , USA and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Futura Publishing, Inc.
    Pacing and clinical electrophysiology 27 (2004), S. 0 
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Little data exists to support the use of procedural modifications during radiofrequency catheter ablation (RFCA) in small children. A single institution database was reviewed for patients under 15 kg undergoing RFCA from January 1998 to August 2001. Of 268 RFCA procedures, 18 were done in 14 patients under 15 kg (median weight 5.7 kg, 3.5–13.7; age 5.8 months, 1.2–19.8). Six patients had normal hearts, 4 had congenital heart disease, and 4 patients had cardiomyopathy. Diagnoses were orthodromic reciprocating tachycardia (ORT) in nine patients/nine studies, chaotic atrial tachycardia (CAT) in one patient/two studies, and VT in four patients/seven studies. RFCA variables included maximum temperature (69°C, 50–78), total applications (10, 2–21), applications 〉 20 seconds (5, 0–15), and total application time (331 s, 26–1,006 s). Complications were pericardial effusion in 1 patient, mild mitral regurgitation in 1, and myocardial infarction in 1 patient. When indexed for weight, the number of applications with a duration 〉 20 seconds in the ORT group was significantly greater in complicated versus uncomplicated procedures (0.7 applications/kg vs 0.16 applications/kg, P = 0.05). In addition, for the ORT subgroup, the indexed total application time trended higher in complicated versus uncomplicated procedures (40.6 s/kg, vs 6.6 s/kg, P = 0.1). RFCA success was 9/9 in ORT, 6/7 in VT, and 0/2 in CAT. RFCA can be successful in small children; however, complications appear to be related to RF dose indexed for body size. Thus, the decision to proceed with RFCA, and the application duration and number should be guided by patient size, balanced against the risks of the arrhythmia, and reserved for dire circumstances. (PACE 2004; 27:224–229)
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An infant with congenital junctional ectopic tachyardia required frequent hospitalizations due to tachycardia acceleration despite multiple antiarrhythmic medications. At 9 months of age, he underwent successful radiofrequency catheter ablation of the tachycardia with preservation of AV conduction.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Pacing and clinical electrophysiology 20 (1997), S. 0 
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Intraatrial reentry tachycardia is a common cause of both morbidity and mortality after surgery for a variety of congenital heart defects. Despite an armamentarium of arrhythmia management tools, including drug therapy, antibradycardia, and antitachycardia pacing, and catheter ablation, management of these arrhythmias remains a challenge. This report briefly reviews the problem, assesses the current successes and failures of radiofrequency catheter ablation for treating it, and discusses a number of ongoing developments that may improve both early and late outcome.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SANATANI, S., et al.: Spontaneously Terminating Apparent Ventricular Fibrillation During Transesophageal Electrophysiological Testing in Infants with Wolff-Parkinson-White Syndrome. This article describes two infants with Wolff-Parkinson-White (WPW) syndrome in whom apparent VF occurred without antecedent AF or atrial flutter during routine transesophageal electrophysiological testing. Remarkably, this arrhythmia terminated spontaneously in both infants. The documentation of self-limited apparent VF, or polymorphic ventricular tachycardia close to VF, in transesophageal testing adds another dimension to the management of WPW.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Bipolar epicardial leads are not yet widely available for atrial use. Since September 1986, we have used a bipolar active fixation endocardial lead (Cardiac Pacemakers model number's 4266, 4268, and 4269) as a bipolar epicardial atrial lead by attaching the corkscrew tip to the atrial surface and imbricating atrial tissue around the more proximal electrode. A total of 77 bipolar epicardial atrial leads have been implanted using this approach in 72 patients with congenital heart disease (ages 3 months to 38.7 years; mean 8.9 ± 8.8 years). Indications for atrial pacing included AV block (n = 46), sinus node dysfunction (n = 17), and antitachycardial pacing (n = 9). Indications for epicardial pacing included the presence of an intracardiac right to left shunt (n = 33), concomitant cardiac surgery (n = 26), surgeon preference (n = 7), and lack of transvenous access to the atrial endocardium (n = 6). Follow-up (median 23 months; mean 28.0 ± 23.1 months; range 1–78 months) data beyond 1 month postimplantation were available for 44 leads. Atrial sensing was ≥ 2.0 mV for 26 leads (59%) with sensing possible at ≥ 0.75 mV for 42 leads (95%). Threshold data were available at 5 V for 37 leads and at 2.5 V for 36 leads with mean pulse width thresholds measuring 0.21 ± 0.33 ms and 0.34 ± 0.34 ms, respectively. Two leads failed (high capture thresholds at 5 days [n = 1], lead fracture at 42 months [n = 1]); one of which was replaced. Four additional leads were replaced electively (marginal thresholds [n = 1], intermittent phrenic nerve stimulation [n = 1], damaged during subsequent surgery [n = 1], clinically irrelevant insulation break [n = 1]) concomitant with additional cardiac surgery. Until a commercially available lead is developed and released, improvisation with a bipolar active fixation endocardial lead as a bipolar epicardial atrial lead is a reasonable approach to providing bipolar atrial sensing and pacing in patients for whom endocardial pacing is contraindicated.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: VAN HARE, G.F., et al.: Prospective Assessment After Pediatric Cardiac Ablation: Design and Imple-mentation of the Multicenter Study. A multicenter prospective study was designed and implemented as an activity of the Pediatric Electrophysiology Society to assess the risks associated with radiofrequency ablation in children. Patients (age 0–15 years) with supraventricular tachycardia due to accessory pathways or atrioventricular nodal reentry were enrolled and studied prior to ablation and periodically by clinical evaluation, electrocardiogram (ECG), Holter monitor, and echocardiogram. In addition, a national registry was established, to which the contributing centers report all pediatric patients undergoing ablation at their center. Initial electrophysiological study tracings and all noninvasive studies undergo blinded outside review for quality control. Clinical endpoints were death, recurrence, proarrhythmia, and echocardiographic abnormality. A pilot study demonstrated excellent agreement concerning diagnoses of previously reported ablation patients between the reporting center and the blinded reviewer (kappa = 0.938 ± 0.062). A total of 317 patients were enrolled in the ongoing study from April 1, 1999 to December 31, 2000. The success rate of ablations was 96% with a complication rate of 4.3% for electrophysiological study and 2.9% for the ablation procedure. Comparison of the registry group versus the study group shows that the groups are comparable in terms of patient characteristics, diagnoses, and the results of ablation making it less likely that the sample of prospectively enrolled patients is biased.
    Type of Medium: Electronic Resource
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