Electronic Resource
Oxford, U.K. and Cambridge, USA
:
Blackwell Science Ltd
Scandinavian journal of immunology
44 (1996), S. 0
ISSN:
1365-3083
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Stressful events induce responses in the endocrine and immune systems. The authors analysed the influence of repetitive noise stress on peritoneal macrophage oxidative and phagocytic responses. Plasma corticosterone levels were also measured. Different groups of 6- to 8-week-old C57BL/6 male mice were exposed for 1 night (n=14) and 3 nights (n=21) to a sound stress of 110 dB in an audiogenic stress chamber. Control animals were submitted to a sham stress for 1 night (n=13) and 3 nights (n=17). A marked decrease was observed in the phagocytic response to yeast (P=3×10−4) while a mild increase in the oxidative response stimulated by opsonized zymosan was noted only after the 3 night stress (P=0.02). Corticosterone levels of control and stressed mice did not differ. These results indicate that the stress resulting from repetitive noise causes modifications in peritoneal macrophage activity, and that these changes are dependant on the duration of stress. These functional alterations seem more complex than a simple general suppression or activation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1046/j.1365-3083.1996.d01-349.x
Permalink
| Library |
Location |
Call Number |
Volume/Issue/Year |
Availability |
