ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
New Zealand virgin rabbits were used in this study. Normal males and castrated, thyroidectomized and recently mated females formed the control groups. Correlation with the light microscopical appearance using the method of alternate thin and thick sections, correlation with the control glands, and comparison with the descriptions in the rat, were used as criteria for the identification of five different types of secretory cells in the pars distalis. Two types of “acidophiles” were found, the more numerous and conspicuous having secretory granules of a maximum diameter of 380-400 mm̈ (growth hormone-producing cell), and a second type with granules of 600-800 mm̈, very seldom seen in the virgin rabbit but increasing in number and granulation after mating (Prolactin-producing cell). Two types of “basophiles” that correspond to the “thyrotrophes” (angular shape, granules of 150 mm̈ in diameter) and “gonadotrophes” (rounded shape, granules of 280-300 mμ), were also identified. In addition, a peculiar large cell with characteristic mottled cytoplasm and very few granules was tentatively identified as a “basophile” in the process of regranulation. Its functional significance was discussed. A stellate cell having fibrillar material and no secretory granules within its cytoplasmic processes, found between parenchymal cells and approaching basement membranes, was tentatively identified as a supporting element. In addition to the description of the fine structure and possible functional significance of the different cell types, some features as cilia, desmosomes, intranuclear fibrillar material, as well as vacuolization of cells in normal glands were also discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091470404
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