ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
3,5-Diamino-4-phenylazo-pyrazoles (1a-1c) react with acetylacetone and with ethyl acetoacetate to yield the corresponding pyrazolo[1,5-a]pyrimidine derivatives 2a-2c and 3a-3c, respectively.Whereas 1a-1c add readily to methyl acrylate yielding the 4,5,6,7-tetrahydropyrazolo[1,5-a]-pyrimidine derivatives 5a-5c, 1a-1c add to methylacrylonitrile or methyl methacrylate only under drastic conditions to yield 5d-5f. The pyrimido[1,2:2′,3′]pyrazolo[1,5-a]pyrimidine derivatives 10a-10c are prepared by the action of acrylonitrile on 2a-2c. Compounds 10a-10c are readily converted into the corresponding oxo derivatives 12a-12c on treatment with acetic acid-hydrochloric acid mixture.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19750580710
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