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  • 1
    Electronic Resource
    Electronic Resource
    High-pressure liquid chromatographic determination of ascorbic acid in selected foods and multivitamin products (1976)
    s.l. : American Chemical Society
    Analytical chemistry 48 (1976), S. 796-798 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60370a025
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The physical nucleon in static source meson theory
    Amsterdam : Elsevier
    Annals of Physics 7 (1959), S. 154-173 
    Details
    ISSN: 0003-4916
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0003-4916(59)90015-6
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  • 3
    Electronic Resource
    Electronic Resource
    Association of CTR and COLIA1 Alleles with BMD Values in Peri- and Postmenopausal Women (2000)
    Springer
    Calcified tissue international 67 (2000), S. 361-366 
    Details
    ISSN: 1432-0827
    Keywords: Key words: COLIA1 — CTR — Genetics — Bone mass — Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. The variability of bone mass and bone strength is in part genetically determined. The pathophysiology of the disease is complex and its heritability is almost certainly polygenic. In a large group of women from north eastern Italy, homogeneous for calcium intake and other risk factors for osteoporosis, we investigated three different genetic polymorphic markers that have been associated with bone mineral density (BMD). The study includes 663 postmenopausal (aged 48–85 years) and 52 perimenopausal (aged 47–53 years) women. Lumbar spine and hip BMD were measured by dual energy X-ray absorptiometry (DXA). After DNA extraction, the restriction enzymes utilized were MscI for the SP1 site of the collagen type I regulatory region (COLIA1), AluI for the calcitonin receptor (CTR) gene, and BsmI for the Vitamin D receptor (VDR) gene. COLIA1 genotype was significantly associated with age-adjusted hip BMD, with the highest values in the SS group and the lowest in the ss group (p 〈 0.05). The COLIA1 effect was not visible until the sixth decade of life, but it increased thereafter with aging, becoming statistically significant also at the lumbar spine in subjects aged 〉70 years. CTR genotype was also significantly related to bone mass in the CC group, with the lowest age and weight-adjusted BMD values at the spine (p 〈 0.05). The CTR genotype effect was greater in the younger subset of women. This suggests that the CTR genotype might influence the process of acquiring peak bone mass rather than the process of bone loss along aging. No trend association was found between BMD values and VDR genotype. These findings suggest an association between the COLIA1 gene polymorphism more with the age-related rate of bone loss than with peak bone mass, which apparently is somewhat affected by CTR gene polymorphism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002230001160
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    MIRVs and the Strategic Balance (1970)
    [s.l.] : Nature Publishing Group
    Nature 228 (1970), S. 53-53 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The measure of stability adopted by Bellany is based solely on the number of warheads that survive a first strike by the opposing power. I shall present several arguments to show why this criterion is unsatisfactory. In the model in which the forces of the two major powers are assumed to be equal, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/228053a0
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  • 5
    Electronic Resource
    Electronic Resource
    Long-Term Persistence of Low Bone Density in Orthotopic Liver Transplantation (2000)
    Springer
    Osteoporosis international 11 (2000), S. 417-424 
    Details
    ISSN: 1433-2965
    Keywords: Key words:Bone turnover – Immunosuppressive drugs – Liver disease – Liver transplant – Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We determined bone density and metabolism in 46 patients (35 males, 11 females) who had undergone liver transplantation 1–48 months previously. Twenty-one patients were then followed for the next 24 months. At each visit, blood and urine samples for bone and liver metabolism parameters, as well as spinal and femoral dual-energy X-ray absorptiometry (DXA) scans, were obtained. Basal spinal and femoral density was low (p〈0.001). Patients with pre-transplant cholestatic diseases had lower spinal density than all the other subjects (p〈0.05) and the cumulative methylprednisolone intake was an independent negative predictor of total hip density (p〈0.02). At baseline, urinary hydroxyproline and N-telopeptide were at the upper normal level and decreased only after 24 months of follow-up (p〈0.05). During the first year of follow-up, femoral density decreased (p〈0.05) and a partial recovery was observed for both spine and femur after 24 months. After 12 months, femoral bone density was negatively associated with serum cyclosporin A levels (p〈0.005) and cumulative methylprednisolone intake (p〈0.05), while the percent decrease in spinal density after the first 12 months was negatively predicted by mean daily methylprednisolone intake (p〈0.05). In patients with pre-transplant cholestatic diseases, femoral and spinal density increased after the first (p〈0.05) and second year (p〈0.05), respectively. In patients with previous post-necrotic cirrhosis, femoral density decreased after 12 months (p〈0.05) and was still lower than baseline after 24 months (p〈0.05). However, at the end of the study the cumulative percentage of femoral neck osteoporosis was 43%. In conclusion, an elevated prevalence of spinal and femoral osteoporosis is present even many years after liver transplantation, with immunosuppressive treatment and pre-transplant liver disease being the most important pathogenetic factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001980070109
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  • 6
    Electronic Resource
    Electronic Resource
    A frontal method based solution of the quasi-three-dimensional finite element model for interconnected aquifer systems. Steady and unsteady equations, with the E.N.S. method for fluid mass balance evaluation (1983)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 3 (1983), S. 445-479 
    Details
    ISSN: 0271-2091
    Keywords: Finite Element ; Quasi-three-dimensional ; Interconnected Aquifer Systmes ; Fluid Mass Balance ; Iterated Frontal Method ; Predictor-Corrector Method ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The quasi-three-dimensional equations controlling the groundwater flow in heterogeneous and interconnected aquifer systems are discretized by finite elements, considering also the aquifer branching. A new method for fluid mass balance evaluation based on the equivalent nodal source (E.N.S.) concept allows one to express the balance in conservative terms, and interpret finite element equations as nodal balance equations. The solution of the system is based on the frontal method. Use of substructures limits the frontal increase in correspondence to the aquifer branching. In the steady state, the frontal method is integrated with an iterative solution technique to eliminate the frontal increase caused by the presence of aquitards. It converges very rapidly, using a forcing technique with an automatic parameter definition. In the unsteady case the same scope is achieved using a predictor-corrector procedure which employs the Crank-Nicolson method in the corrector phase.This very stable procedure permits use of fairly long time-steps and concerns the case of source terms depending on piezometry (problem of interaction between water table and river). This method has been tested with several fairly complex cases.
    Additional Material: 21 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650030503
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