ISSN:
1440-1681
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
1. An assessment was made of the extent sodium (Na) and potassium (K) intake can be estimated from Na, K and creatinine (Cr) content of a second morning voiding urine (SMU) specimen collected within 4 h after the first voiding upon awakening but before breakfast in 159 clinically healthy, free-living individuals (20–79 years). The SMU and the rest of 24 h urine specimens for a 3–5 day period were collected.2. The following equations for estimating 24 h urinary Na (24HUNaV) and K (24HUKV) excretions were developed, and the accuracy and the reliability of these equations were evaluated. Estimated value of 24HUNaV (mEq/day) = 16.3 √XNa; estimated value of 24HUKV (mEq/day) = 7.2 √XK, where XNa (or XK) = SMUNa (or SMUK)/SMUCr X predicted 24 h urinary Cr excretion.3. Highly statistically significant correlations were detected between the values estimated and measured for both Na (r= 0.728, P 〈 0.001, n= 159) and K (r= 0.780, P 〈 0.001, n= 159).4. These equations were applied to Group 1 subjects, who collected the urine for a single day, and to Group 2, for 3 days. The correlation coefficients between the values estimated and measured for Na and K were 0.531 and 0.443 in Group 1, and 0.821 and 0.590 in Group 2, respectively. No statistically significant differences were observed.5. The SMU specimens provide a satisfactory alternative to both 24HUNaV and 24HUKV in adults for extensive epidemiological surveys but also for clinical application.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1440-1681.1993.tb01496.x
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