ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Weanling male and female littermate Osborne Mendel rats were randomly separated into two groups. The control group was fed a grain ration. The second group was fed a high fat ration which ultimately produced obesity. Male and female rats were killed at weaning (body weight, 50-60 gm). Thereafter rats from both diet groups were killed after an initial weight gain of about 100 gm and subsequent gains of about 150 gm. The inguinal, forelimb (axillary), interscapular perirenal, genital, xiphoid, and mesenteric and omental fat depots were removed, weighed, and weights recorded. Fat depots usually increased in weight more rapidly than overall body weight. This was typical of younger rats from both diet groups, but more pronounced in rats fed the high fat ration. The perirenal depots increased in weight more rapidly than body weight throughout the 450+ days of the study. In both sexes and diet groups, from weaning through sexual maturity, the weight of the genital fat depots increased proportionately more rapidly than body weight. Thereafter, the weight gain more nearly paralleled the body weight gain. In both diet groups, with the exception of the interscapular depot, the subcutaneous depots increased rapidly in weight during the first 100 days of life. The weight gain of these depots maintained a close relationship to body weight gain after 100 days of age. The interscapular depot in obese females increased at a very rapid rate as the animals approached 900 gm of body weight.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091660303
Permalink
