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  • 1
    Electronic Resource
    Electronic Resource
    Biological effects of singlet delta oxygen on respiratory tract epithelium (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 514-515 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Exposure of hamster tracheal organ cultures to gas phase singlet delta oxygen,1O2, at atmospheric pressure produced significant alterations in the mucociliary epithelium resulting in changes in ciliary activity and cellular morphology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01952414
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Incorporation of3H-Uridine into bovine cells doubly infected with the virus of bovine viral diarrhea and a bovine enterovirus (1972)
    Springer
    Archives of virology 36 (1972), S. 226-231 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Tritiated uridine was selectively incorporated into the cytoplasm but not the nucleus of BEK cells infected with bovine enterovirus. This was accompanied by complete shutdown of cellular RNA synthesis. Bovine embryonic spleen cells infected with the BVD virus incorporated3H-uridine into the nucleus and cytoplasm, while uninfected cells showed only nuclear and nucleolar incorporation. Bovine embryonic spleen cells that were preinfected with BVD virus for 20 hours and then superinfected with bovine enterovirus showed complete absence of nuclear and nucleolar labelling in the early stages of superinfection with the bovine enterovirus, but nuclear labelling returned in reduced amounts 8 to 10 hours after superinfection and persisted throughout the remainder of the double infection ending in cell death.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01249853
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  • 3
    Electronic Resource
    Electronic Resource
    Kinetics of virus production in cells doubly infected with the virus of bovine diarrhea and a bovine enterovirus (1972)
    Springer
    Archives of virology 36 (1972), S. 218-225 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary One-step growth curves of a bovine enterovirus and the virus of bovine diarrhea (BVD) in singly and doubly infected bovine embryonic kidney (BEK) and bovine embryonic spleen (BES) cells were determined. In BEK cells, bovine enterovirus infectivity increased exponentially in both tissue culture fluid and cells 4 to 10 hours after inoculation and then levelled off. In BES cells, the exponential increase lasted 14 to 17 hours. In the growth curve of the BVD virus in BEK cells, the extracellular and cell-associated viruses increased exponentially until hour 12, increasing gradually thereafter. In BES cells, BVD virus infectivity increased exponentially 24 hours after infection and then levelled off. The peak infectivity in BES cells was reached 24 hours before that in BEK cells. Growth of bovine enterovirus was studied in cells of BEK and BES monolayers preinfected with the BVD virus for 20 hours. The infectivity titer in preinfected BEK cells was approximately 2 logs less than in preinfected BES cells. A decreased yield in infectivity was observed compared to the bovine enterovirus one-step growth curve.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01249852
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Studies on the mechanisms of influenza virus infection in hamster trachea organ culture (1974)
    Springer
    Archives of virology 44 (1974), S. 195-204 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Tracheal organ cultures of 4-day-old, 2-, and 4-week-old Syrian hamsters infected with influenza A/PR/8 virus were studied. Ciliary activity in infected explants from 4-day-old and 2-week-old hamsters declined rapidly after five days and by the 13th day was virtually undetectable. Cultures from 4-week-old hamsters showed a similar but slower effect. Histological sections of infected explants showed distinct cytopathologic changes which preceded ciliostasis. The columnar structure of the ciliated respiratory epithelium in all infected tracheal tissue became flattened and was eventually destroyed. When influenza A/PR/8 virus was added to whole tracheal explants from 4-day-old hamsters, approximately 70 per cent of the virus adsorbed in the first 30 minutes, and 90 per cent of the total adsorbed within 2 hours. Explants from 2- and 4-week-old hamsters adsorbed influenza virus at a much slower rate. Growth curves indicated that tracheal cultures from all three age groups support replication of A/PR/8 virus. Explants from 4-day-old hamsters yielded a maximum titer of 103.75HAD50/ml by the 9th day after injection; cultures from 2- and 4-week-old hamsters yielded a 5 and 15-fold lower infectivity titer. Interferon was demonstrated in infected cultures from the three different age groups in comparable concentrations.In vivo studies indicate that 4-day-old hamsters have a greater susceptibility than 2- and 4-week-old hamsters to hamsters-adapted influenza A/PR/8 virus. Observations from cultures of young suckling hamster tracheas indicate this model system will be useful in further investigations of tissue specificity in influenza viral infections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01240607
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  • 5
    Electronic Resource
    Electronic Resource
    The structure of [YC6H5O]+· ions in the spectra of aryl alkyl ethers (1969)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 2 (1969), S. 757-759 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The [YC6H5O]+· ions from YC6H4OC2H5 appear to correspond in structure to the molecular ions of the analogous substituted phenols, [YC6H4OH]+·.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210020711
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    Paper (German National Licenses)
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