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  • 1
    Electronic Resource
    Electronic Resource
    Nachtrag zum Aufsatz: Mehrfaserige (»polyine«) subepitheliale Muskelzellen bei Hydromedusen (Carmarina) in Arch. f. mikroskop. Anat. Bd. 93, Abt. I (1920), S. 456 (1924)
    Springer
    Development genes and evolution 101 (1924), S. 455-457 
    Details
    ISSN: 1432-041X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02108175
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Über das Epithel der Haftscheibe von Liparis montagui Donovan (1937)
    Springer
    Anatomy and embryology 107 (1937), S. 223-230 
    Details
    ISSN: 1432-0568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Das vielschichtige Epithel des Randgebietes der Haftscheibe vonLiparis montagui Donovan besitzt eine eigentümliche cuticulare Deckschicht; diese kommt so zustande, daß jede oberflächliche Zelle einen langen und dünnen protoplasmatischen Fortsatz ausschickt, der eine röhrenförmig-prismatische Scheide liefert. Wie der Übergang zu dem gewöhnlichen Epithel lehrt, entspricht diese Deckschicht der cuticularen Lamelle des gewöhnlichen Epithels oberhalb des Stäbchensaumes. Sie erreicht aber im Randgebiet nicht nur bedeutende Dicke, sondern zugleich wird ihr durch die Zellfortsätze die geschilderte Form aufgezwungen. Die Bildung der Fortsätze stellt also eine eigenartige Form der Oberflächenvergrößerung dar, welche die Abscheidung der überall vorhandenen cuticularen Lamelle in besonderem Ausmaß gestattet. Das Epithel und auch die Zellfortsätze werden von reichlichen Tonofibrillen durchzogen, die sich zwischen gekreuzten Nicols leicht nachweisen lassen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02120120
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  • 3
    Electronic Resource
    Electronic Resource
    Einiges Über die Entwickelung der Guanophoren bei den Amphibien (1920)
    Springer
    Anatomy and embryology 59 (1920), S. 293-319 
    Details
    ISSN: 1432-0568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02047520
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Beobachtungen an den roten Chromatophoren in der Haut von Rana fusca (1920)
    Springer
    Anatomy and embryology 58 (1920), S. 641-671 
    Details
    ISSN: 1432-0568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02071044
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  • 5
    Electronic Resource
    Electronic Resource
    Über den Feinbau tierischer Fibrillen (1924)
    Springer
    Naturwissenschaften 12 (1924), S. 269-275 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01506180
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  • 6
    Electronic Resource
    Electronic Resource
    Fehlt dem menschlichen Haar eine Cuticula (Epidermicula), sind die Elemente seiner Rinde zopfartig verflochten? (1923)
    Springer
    Archives of dermatological research 144 (1923), S. 237-250 
    Details
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01987046
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  • 7
    Electronic Resource
    Electronic Resource
    Einiges über optische Anisotropie und Feinbau von Chromatin und Chromosomen (1941)
    Springer
    Chromosoma 2 (1941), S. 86-110 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Im Hinblick auf die Darstellung Casperssons s1 wird folgendes herausgestellt: 1. Eine nähere Prüfung des Verhaltens isotropen oder positiv doppelbrechenden chromatischen Materials (Isosporenkerne von Radiolarien, Spermienköpfe) lehrt, daß das Auftreten negativer Doppelbrechung nach Behandlung mit Alkohol keineswegs stets auf Orientierung vorher wirrer Nucleinsäureketten zu beruhen braucht, vielmehr in den genannten Fällen feinbauliche Ordnung (Faserstruktur) vorausgesetzt werden muß, trotz Mangels von (negativer) Doppelbrechung. 2. Es werden die Gründe zusammengestellt, die eine solche Erklärung auch für das Chironomuschromosom näher legen als Casperssons Deutung. 3. Es wird gezeigt, daß Caspersson die Leistungsfähigkeit der polarisationsmikroskopischen Untersuchung im gewöhnlichen Licht bedeutend unterschätzt hat; sie ist dem Casperssonschen Verfahren der Untersuchung des ultravioletten Dichroismus nicht wesentlich unterlegen, zumal in die Überlegungen casperssons betreffend Ordnungsgrad Faktoren eingehen, die zur Zeit noch nicht quantitativ erfaßt werden können. 4. Es wird die Leistungsfähigkeit der polarisationsmikroskopischen Untersuchung in gewöhnlichem Licht an Photogrammen von Spermien vorgeführt und der Wunsch ausgesprochen, daß zum Zweck des Vergleiches entsprechende Aufnahmen der dichroitischen ultravioletten Absorption hergestellt werden mögen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00325955
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  • 8
    Electronic Resource
    Electronic Resource
    Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats (2003)
    Oxford, UK : Blackwell Science, Ltd
    European journal of neuroscience 17 (2003), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Parkinson's disease is characterized not only by a progressive loss of dopaminergic neurons in the substantia nigra but also by a degeneration of locus coeruleus noradrenergic neurons. The present study addresses the question of whether a partial neurodegeneration of dopaminergic neurons using 6-hydroxydopamine in rat, not sufficient to produce motor disturbances, is potentiated by prior selective denervation of locus coeruleus noradrenergic terminal fields using N-ethyl-2-bromobenzylamine. Two types of denervations, one causing dopamine deficiency alone and the other causing noradrenaline and dopamine deficiency, were performed. Noradrenaline, 5-hydroxytryptamine, 5-hydroxyindole acetic acid, dopamine and its metabolites were analysed in various brain regions. Behaviour was evaluated by catalepsy tests and activity box. N-ethyl-2-bromobenzylamine selectively depleted noradrenaline from neurons of locus coeruleus origin. Decreased dopamine content in the striatum, substantia nigra and pre-frontal cortex was observed after dopaminergic lesion with 6-hydroxydopamine (42.9%). Additional locus coeruleus noradrenaline depletion with N-ethyl-2-bromobenzylamine aggravated the dopamine depletion (61.2%). The lesion in the noradrenergic and dopaminergic neurodegenerated group was not sufficient to induce consistent catalepsy and akinesia. However, after a subthreshold dose of haloperidol (0.1 mg/kg), the expression of catalepsy and akinesia was strong in the dual-lesioned group and less in the 6-hydroxydopamine-lesioned group. These results indicate that denervation of locus coeruleus noradrenergic terminals with N-ethyl-2-bromobenzylamine potentiates the 6-hydroxydopamine-induced partial dopaminergic neurodegeneration and parkinsonian symptoms. Based on the present findings and existing reports, it can be concluded that noradrenergic neurons of locus coeruleus have neuromodulatory and neuroprotective properties on the dopaminergic neurons of basal ganglia and that noradrenergic degeneration may contribute to the aetiology and pathophysiology of Parkinson's disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9568.2003.02684.x
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  • 9
    Electronic Resource
    Electronic Resource
    Flupirtine: A Review of Its Neuroprotective and Behavioral Properties (1998)
    Oxford, UK : Blackwell Publishing Ltd
    CNS drug reviews 4 (1998), S. 0 
    Details
    ISSN: 1527-3458
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1527-3458.1998.tb00061.x
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  • 10
    Electronic Resource
    Electronic Resource
    Dopamine-glutamate interactions in the basal ganglia (1998)
    Springer
    Amino acids 14 (1998), S. 5-10 
    Details
    ISSN: 1438-2199
    Keywords: Basal ganglia loops ; Reward ; Sensitization ; NMDA receptor ; Parkinson's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In an attempt to formulate a working hypothesis of basal-ganglia functions, arguments are considered suggesting that the basal ganglia are involved in a process of response selection i.e. in the facilitation of “wanted” and in the suppression of “unwanted” behaviour. The meso-accumbal dopamine-system is considered to mediate natural and drug-induced reward and sensitization. The meso-striatal dopamine-system seems to fulfill similar funcions: It may mediate reinforcement which strengthens a given behaviour when elicited subsequently, but which is not experienced as reward or hedonia. Glutamate as the transmitter of the corticofugal projections to the basal ganglia nuclei and of the subthalamic neurons is critically involved in basal ganglia funcions and dysfunctions; for example Parkinson's disease can be considered to be a secondary hyperglutamatergic disease. Additionally, glutamate is an essential factor in the plasticity response of the basal-ganglia. However, opposite to previous suggestions, the NMDA-receptor blocker MK-801 does not prevent psychostimulant- nor morphine-induced day to day increase (sensitization) of locomotion. Also the day to day increase of haloperidol-induced catalepsy was not prevented by MK-801.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01345235
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