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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 13 (1974), S. 163-169 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 8 (1992), S. 514-517 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 3 (1987), S. 1128-1131 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 3 (1987), S. 1131-1135 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0533
    Keywords: Key words Spinal cord injury ; Stroke ; B7 molecules ; Macrophage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Lesion-induced microglial/macrophage responses were investigated in post-mortem human spinal cord tissue of 20 patients who had died at a range of survival times after spinal trauma or brain infarction. Caudal to the spinal cord injury or brain infarction, a strong increase in the number of activated microglial cells was observed within the denervated intermediate grey matter and ventral horn of patients who died shortly after the insult (4–14 days). These cells were positive for the leucocyte common antigen (LCA) and for the major histocompatibility complex class II antigen (MHC II), with only a small proportion staining for the CD68 antigen. After longer survival times (1–4 months), MHC II-immunoreactivity (MHC II-IR) was clearly reduced in the grey matter but abundant in the white matter, specifically within the degenerating corticospinal tract, co-localising with CD68. In this fibre tract, elevated MHC II-IR and CD68-IR were still detectable 1 year after trauma or stroke. It is likely that the subsequent expression of CD68 on MHC II-positive microglia reflects the conversion to a macrophage phenotype, when cells are phagocytosing degenerating presynaptic terminals in grey matter target regions at early survival times and removing axonal and myelin debris in descending tracts at later survival times. No T or B cell invasion or involvement of co-stimulatory B7 molecules (CD80 and CD86) was observed. It is possible that the up-regulation of MHC II on microglia that lack the expression of B7 molecules may be responsible for the prevention of a T cell response, thus protecting the spinal cord from secondary tissue damage.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract During commercial handling of Nephropsnorvegicus (L.) there are a number of situations when the prawns may be exposed to very high ambient ammonia levels. These experiments evaluated the effects of increased levels of ambient total ammonia (TA = NH3 + NH4 +) on␣blood ammonia, ammonia efflux rates and on the cardio-ventilatory performance of N. norvegicus. When prawns were taken from 〈1 to 2000 μmol TA l−1 medium, blood TA concentrations increased rapidly for the first 2 h but tended to drop thereafter. Original blood TA levels were restored 6 h after the prawns were transferred back from seawater containing 2000 to 〈1 μmol TA l−1. Sudden exposure to 500, 1000, 2000 or 4000 μmol TA l−1 medium induced blood TA concentrations to increase respectively to 50, 30, 33 and 36% of external concentrations (normally, internal TA values are much higher than external levels). Immediately after transfer back to seawater with low ammonia concentration ( 〈1 μmol TA l−1), excretion rates were higher than those of control prawns, and the absolute amounts of TA excreted were considerably higher than those calculated to have accumulated in the haemolymph. Heart rate (HR) and scaphognathite rate (SR) were not altered when prawns were subjected to sudden alterations in ambient ammonia ( 〈1 to 2000 to 〈1 μmol TA l−1). When water ammonia concentrations were altered more gradually, both rates increased, but only at 4000 μmol TA l−1. These results show that N. norvegicus is able to remove ammonia from the haemolymph and/or transform ammonia into some other substance when subjected to increased levels of ambient ammonia. Possible mechanisms involved (e.g. active transport across the gills; storage in some other tissue; glutamate synthe sis) are discussed.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 127 (1997), S. 403-410 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Nephropsnorvegicus (L.) were subjected to 8 h of emersion, either between layers of seawater-soaked hessian with periodical (20 min) flushes of seawater (high humidity, HH) or to unprotected emersion (low humidity, LH). Blood ammonia levels rose during emersion in both groups but reached higher levels under LH conditions. Ammonia efflux rates after re-immersion were higher than those of control prawns, and amounts of ammonia excreted at such times were considerably higher than those calculated to have accumulated in the blood during emersion. Possible explanations for such differences are discussed. C aO2 and C vO2 decreased rapidly to ca. 10% normoxia values within 2 h of HH and LH emersion and remained low throughout the remaining emersion time. Emersion-induced tissue hypoxia increased blood concentrations of glucose and lactate. Lactate accumulation was higher during LH emersion, compared with HH emersion. Blood pH dropped ca. 0.40 units but increased again after 2 h of re-immersion. Acidosis was probably related more to respiratory difficulties (CO2 accumulation) than to lactate accumulation, as blood lactate values remained high after 2 h of re-immersion. The ability of N. norvegicus to cope with emersion appears to be little influenced by high humidity conditions.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 22 (1980), S. 137-143 
    ISSN: 1432-0630
    Keywords: 61.70.Tm ; 61.80.Jh ; 61.70.Ph
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract A method is presented for avoiding the dislocation generation in (100) silicon implanted with phosphorus doses up to 5×1015 ions/cm2 at 50 keV. The residual defects after the damage anneal are considerably reduced if the phosphorus implant is combined with a low dose, e.g. 1×1014 ions/cm2, antimony implant which produces a deeper surface layer of amorphous silicon. It is essential that the phosphorus ions are implanted shallower than the antimony ions, and come to rest within the amorphous layer. Subsequent thermal annealing proceeds by a solid phase epitaxial regrowth mechanism.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 141 (1999), S. 1049-1054 
    ISSN: 0942-0940
    Keywords: Keywords: Craniopharyngioma; cognitive deficits; quality of life.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  The optimal management of craniopharyngioma today remains an unconcluded debate. This prospective study examines the cognitive status and quality of life of 22 patients one year after surgery for craniopharyngioma.  Pterional approach (5 left, 15 right) was used in 20 patients (90%), whereas two were operated on using a rhinoseptal approach.  Neuropsychological examination was performed twelve months after the operation. For twelve patients, neuropsychological examination was performed before operation.  The preoperative evaluation revealed that six patients had impaired neuropsychological testing with memory and frontal dysfunction. Four of these patients have no postoperative neuropsychological defect.  After surgery, there were 5 patients in whom abnormalities could be detected on the extended psychometric assessment: two were severe (a Korsakoff's syndrome and a memory defect associated with an intellectual deterioration), and three moderate (recent memory defects with frontal dysfunction, isolated learning defects). Four patients of the 22 were not able to return to their pre-illness activity.  The present evaluation emphasizes that a good quality of life and neuropsychological performance were maintained in the majority of patients. Preoperative frontal dysfunction is probably correlated to tumour location, and precisely to the interruption of the direct efferent projections from the frontal cortex to the hypothalamus.  Postoperative alterations of neuropsychological function were noticed only in patients with pterional approach. These patients had a poor surgical outcome, preoperative neuropsychological defects or treatment combined with radiotherapy. The two patients who were operated on using a rhinoseptal approach had no neuropsychological deficit. But this surgical approach is best reserved for patients with smaller intrasellar tumours. Further studies are needed to evaluate the neuropsychological advantage of these different approaches.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part D, 19 (1991), S. 885-890 
    ISSN: 1359-0189
    Keywords: High-energy implantation ; hardness ; strain ; surface roughness ; titanium
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Type of Medium: Electronic Resource
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