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  • 1
    Electronic Resource
    Electronic Resource
    Carbon-13-proton spin-spin coupling. 9. Purine (1982)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 104 (1982), S. 4167-4173 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00379a020
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  • 2
    Electronic Resource
    Electronic Resource
    Dissection of the vertebral artery with cervical nerve root lesions (1996)
    Springer
    Journal of neurology 243 (1996), S. 121-125 
    Details
    ISSN: 1432-1459
    Keywords: Vertebral artery dissection ; Cervical nerve root compression ; Nuchal pain ; Colour-coded Duplex sonography ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Vertebral artery dissection may cause upper limb peripheral motor deficit. We report three young patients presenting with nuchal pain followed by a nearly painless proximal paresis of the arm several days later. The cause, as detected by colour-coded Duplex sonography and MRI, was an extracranial dissection of the vertebral artery. The proximity of the intervertebral segment to the vertebral artery and the nerve roots indicated that compression by an intramural haematoma was the likely cause of the disorder. Subsequent examinations during anticoagulation treatment showed almost complete disappearance of the intramural haematoma and of the neurological deficits within a few weeks. We believe that the occurrence of an upper limb peripheral motor deficit should be added to the spectrum of potentially misleading signs of vertebral artery dissection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02444001
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  • 3
    Electronic Resource
    Electronic Resource
    Ein Pólyasches Momentenproblem und umhüllende asymptotische Potenzreihen (1975)
    Springer
    Mathematische Zeitschrift 145 (1975), S. 231-234 
    Details
    ISSN: 1432-1823
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01215287
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Oxygen-17 NMR relaxation times of the protein amino acids in aqueous solution: estimation of the relative hydration numbers in the cationic, anionic, and zwitterionic forms (1991)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 95 (1991), S. 3804-3811 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100162a067
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Der Zerfall des 4,4 min-Rh104m (1965)
    Springer
    The European physical journal 185 (1965), S. 60-72 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The decay of the 4.4 min-Rh104m has been investigated by observing coincidences between conversion electrons and gamma quanta. The decay by a 77 keV−52 keV cascade has been confirmed. In addition, a highly converted (31±2) keV transition in coincidence with the known 97 keV gamma ray has been found. The multipole order of this transition has been determined asM3. The intensity of the 97 keV−31 keV cascade has been measured as 3.3 % of the intensity of the 77 keV−52 keV cascade. An indication of a 45 keV transition from the 97 keV level to the 52 keV level has been found with an intensity of at most 0.1 % of the intensity of the 77 keV−52 keV cascade.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01381303
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Vein Graft-Coated Vascular Stents: A Feasibility Study in a Canine Model (1998)
    Springer
    CardioVascular & interventional radiology 21 (1998), S. 158-164 
    Details
    ISSN: 1432-086X
    Keywords: Key words: Arteries—Vein grafts—Interventional instrumentation—Stents, experimental—Animal studies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: To evaluate different vein grafts for luminal coating of endovascular stents in normal canine arteries. Methods: Twenty-four tantalum Strecker stents were coated with either autologous (n= 10), denatured heterologous (n= 11), or denatured homologous vein grafts (n= 3). The carotid artery (n= 11) and the iliac artery (n= 13) were stented using a transfemoral approach. Angiograms were performed at days 0, 7, and 21, and months 3, 6, and 9. All grafts underwent histological examination. Results: Eight of 10 autologous vein grafts showed patency during the whole observation period of 9 months, without histological signs of inflammation. Denatured heterologous vein grafts revealed acute (n= 3), subacute (n= 5), or delayed (n= 3) vessel occlusion. Hyaloid transformation of the vein graft and lympho-plasmacellular formations were seen. Denatured homologous vein grafts showed acute vessel occlusion. Although significant inflammatory tissue response was seen, no host-versus-graft reaction was present. Conclusion: Autologous vein graft-coated stents showed good biocompatibility in canine arteries. Preparation was cumbersome and required surgical venae-sectio. Denatured vein grafts, however, were limited by inflammatory reactions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002709900234
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  • 7
    Electronic Resource
    Electronic Resource
    Asymptotische Potenzreihen in zwei Veränderlichen (1979)
    Springer
    Archiv der Mathematik 32 (1979), S. 377-384 
    Details
    ISSN: 1420-8938
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01238514
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Early-onset Alzheimer’s disease due to mutations of the presenilin-1 gene on chromosome 14: a 7-year follow-up of a patient with a mutation at codon 139 (1998)
    Springer
    European archives of psychiatry and clinical neuroscience 248 (1998), S. 123-129 
    Details
    ISSN: 1433-8491
    Keywords: Key words Early-onset Alzheimer’s disease ; Presenilin-1 ; Chromosome-14 ; Myocloni
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mutations in the presenilin-1 gene (PS-1 gene) on chromosome 14 have recently been identified as a cause of familial early-onset Alzheimer’s disease (EOAD). To our knowledge, only two German EOAD patients with mutations in the PS-1 gene have been identified thus far. Herein we report the case of a German EOAD patient with a family history of dementia and a missense mutation at codon 139 (M139V) of the PS-1 gene. The patient came to our clinic for the first time when he was 44 years old. During the following 7 years, his Mini-Mental State Examination (MMSE) score dropped from 24 to 0. Myocloni were an early neurological symptom that was already present during the first consultation. We could demonstrate that myoclonic activity was of cortical origin using a back-averaging method. Magnetic resonance imaging (MRI) revealed only slight changes in the early stage of the disease. Follow-up MRI studies showed progression of bitemporal ventricular enlargement and progressive frontal and temporal cortical atrophy. Although the majority of EOAD patients belong to the sporadic (non-genetic) type of AD, early-onset dementia, early myocloni and a familial history of AD should direct attention to the possibility of a genetic form of AD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004060050028
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  • 9
    Electronic Resource
    Electronic Resource
    Traumatic lesions of the optic, oculomotor, trochlear, and abducens nerves — Computer tomographic findings (1988)
    Springer
    Neurosurgical review 11 (1988), S. 231-237 
    Details
    ISSN: 1437-2320
    Keywords: Abducens nerve ; computer-assisted tomography ; multiple injuries ; traumatic lesions ; optic ; oculomotor ; trochlear nerves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Traumatic lesions of the oculomotor and optic nerves are usually associated with multiple injuries which pose difficulties for radiological examination. In 54 patients with functional disturbances of the optic, oculomotor, trochlear, or abducens nerve following severe multiple injuries, the initial computer tomographic examination was unable to document conclusively direct nerve damage. Indirect signs of nerve damage in the form of orbital and midface fractures were often found in the presence of optic and oculomotor nerve impairments, but seldom in the case of abducens nerve deficits. The causes of trochlear pareses could not be established. Thus, CT can only provide indirect evidence of injuries to the optic and oculomotor nerves. The nerve damage itself can only be demonstrated in a target examination made after the patient's condition has stabilized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01741414
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  • 10
    Electronic Resource
    Electronic Resource
    Estimation of prolongation of hospital stay attributable to nosocomial infections: New approaches based on multistate models (1996)
    Springer
    Lifetime data analysis 2 (1996), S. 219-240 
    Details
    ISSN: 1572-9249
    Keywords: Extra hospital stay ; Markov processes ; Multistate models ; Structured nested failure time models ; Time-dependent covariates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Evaluation of the impact of nosocomial infection on duration of hospital stay usually relies on estimates obtained in prospective cohort studies. However, the statistical methods used to estimate the extra length of stay are usually not adequate. A naive comparison of duration of stay in infected and non-infected patients is not adequate to estimate the extra hospitalisation time due to nosocomial infections. Matching for duration of stay prior to infection can compensate in part for the bias of ad hoc methods. New model-based approaches have been developed to estimate the excess length of stay. It will be demonstrated that statistical models based on multivariate counting processes provide an appropriate framework to analyse the occurrence and impact of nosocomial infections. We will propose and investigate new approaches to estimate the extra time spent in hospitals attributable to nosocomial infections based on functionals of the transition probabilities in multistate models. Additionally, within the class of structural nested failure time models an alternative approach to estimate the extra stay due to nosocomial infections is derived. The methods are illustrated using data from a cohort study on 756 patients admitted to intensive care units at the University Hospital in Freiburg.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00128975
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