ISSN:
1434-0879
Keywords:
Benign prostatic hypertrophy
;
Oncornavirus-like proteins
;
Radioimmunoassay
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A sensitive competition radioimmunoassay using 125I-labelled p 30 interspecies antigen, antiserum specific to the interspecies antigen of the feline leukaemia virus, and aqueous tissue extracts from prostate was used to examine benign hyperplastic prostates for the presence of protein components able to compete with the interspecies viral antigens. Six of 20 prostatic nodular hyperplastic tissues were competitive in radioimmunoassay with the 125I-labelled viral antigen for binding sites on the antiviral antibodies. These findings suggest the presence of oncornavirus-like proteins in prostatic nodular hyperplasia. No correlation could be made between the presence of competing protein and histological features of acute or chronic prostatitis and squamous metaplasia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00256132
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