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  • 1
    Electronic Resource
    Electronic Resource
    The future of gross anatomy teaching (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Clinical Anatomy 8 (1995), S. 294-296 
    Details
    ISSN: 0897-3806
    Keywords: survey ; graduate student teaching ; anatomy ; Life and Medical Sciences ; Miscellaneous Medical
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A survey of U. S. departments of anatomy, physiology, and biochemistry shows that 39% of the respondent anatomy departments reported declines in the numbers of graduate students taking the human gross anatomy course. Similarly, 42% of the departments reported decreases in the numbers of graduate students teaching human gross anatomy. These decreases were greater in anatomy than in physiology and in biochemistry. The percentages of departments reporting increases in students taking or teaching their courses was 6% for human gross anatomy and 0% to 19% for physiology and biochemistry courses. To reverse this trend the establishment of specific programs for the training of gross anatomy teachers is advocated. These new teachers will be available as the need for them is increasingly recognized in the future. © 1995 WiIey-Liss, Inc.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ca.980080409
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  • 2
    Electronic Resource
    Electronic Resource
    Specific granules of the rat atrial muscle cellSupported by NIH grant RR5576 and grants from the American Heart Association, Middlesex County Chapter and the Essex County Heart Association. (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 194 (1979), S. 587-601 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The specific granules found in the atrial cardiac muscle cells of the normal rat were studied. The ultrastructural appearance of these granules demonstrates a fixative-dependent lability. Fixation with cacodylate buffered aldehydes yields three types of granules. However, fixation with phosphate buffered aldehvdes or primary fixation with OsO4 yields granules of uniform appearance. The granules are found predominantly in the perinuclear zone; 78% of the granules are within ten linear micrometers of the center of the nucleus. Two independent methods of measurement demonstrate spherical diameters of these granules of 0.30 μm and 0.37 μ respectively. The granules are found in greater concentration at one pole of the nucleus than at the other. On the high density side there are 4.07 granules/μm3 which occupy 5.8% of the cytoplasmic volume. On the low density side there are 2.15 granules/μm3 which occupy 3.0% of the cytoplasmic volume. The granules at both poles are the same size. Atrial walls were incubated in a modified Tyrode's solution. One hour of incubation caused no change in the atrial granules. Addition of norepinephrine or L-Dopa resulted in the appearance of more granules but the size of the granules remained the same. Incubation with reserpine had no effect upon the atrial granules. Apparently the atrial myocardial cell is stimulated by exogenous catechol-amine to synthesize more atrial granules which themselves do not appear to contain catecholamines.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091940411
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of colchicine on myofilament arrangement and the lysosomal system in skeletal muscle (1973)
    Springer
    Cell & tissue research 144 (1973), S. 467-473 
    Details
    ISSN: 1432-0878
    Keywords: Muscle ; Colchicine ; Myofibrils ; Acid phosphatase ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Colchicine was intraperitoneally administered chronically to adult male Sprague-Dawley rats. The ultrastructural study of hind-limb muscles revealed that myofilament desorientation resulted. Bundles of myofilaments were found coursing perpendicular or oblique to the longitudinal axis of the muscle fiber. It is concluded that a colchicine-sensitive factor is involved in maintaining normal orientation of myofibrils in mature muscle. Also found in the sarcoplasm of the colchicine treated animals were complex spheromembranous bodies. These bodies enveloped mitochondria or other organelles and appeared to be derived from the sarcoplasmic reticulum. The lysosomal nature of these bodies is indicated by the localization of acid phosphatase activity in them. Acid phosphatase activity was also displayed in the sarcoplasmic reticulum. The spheromembranous bodies seem to be part of a sarcotubulo-lysosomal system in skeletal muscle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307374
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  • 4
    Electronic Resource
    Electronic Resource
    Slow muscle fibers in the tensor tympani muscle of the guinea pigSupported by N. D. E. A. Title IV Fellowship 67-09956 and U.S.P.H.S. grant 5-TO1-GM 1410-03, 04, 05. (1971)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 132 (1971), S. 267-273 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The tensor tympani muscle of the adult guinea pig was studied by light and electron microscopy. Extrafusal muscle fibers with centrally located nuclei were found. On the basis of morphological criteria, they were considered to be slow muscle fibers and others, with typical peripheral nuclei, twitch muscle fibers.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001320211
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  • 5
    Electronic Resource
    Electronic Resource
    A quantitative analysis of muscle cell changes in compensatory hypertrophy and work-induced hypertrophySupported by NIH Grant RR 5576. (1976)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 145 (1976), S. 459-465 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The cytological characteristics of two modes of muscle hypertrophy were studied in the extensor digitorum longus muscle of the rat. Compensatory hypertrophy (CH) was produced by tenotomy of the tibialis anterior muscle and work-induced hypertrophy (WIH) was produced by forced swimming of the animal. While both methods produced an increase in muscle weight and cell size, these two parameters did not correlate. Morphometric analyses of the hypertrophied muscle cells demonstrated that in CH-muscle there was an increase in mitochondrial volume density, a decrease in myofibrillar volume density and no change in sarcotubular or nuclear volume density. WIH-muscle demonstrated an increase in sarcotubular volume density but no change in mitochondrial, myofibrillar or nuclear volume density. It is concluded that in CH-muscle, the cell volume increase is attributable to mitochondrial volume increase and that there is no increase in the contractile myofibrillar component of the cell. WIH-muscle, on the other hand, has a cell volume increase which is attributable to a proportional increase in these organelles.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001450405
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