ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The osteoblast adhesion to the substrates are recognized to play a fundamental role inosteoconduction process. The purpose of this study was to evaluate the in vitro behavior ofosteoblasts cultured on polarized hydroxyapatite (HA), having the enhanced osteobonding abilities.Osteoblast-like cells were seeded onto the polarized HA and investigated the adhesion and motility.The polarization had no effects on the percentage of the number of the spreaded cells against all theadhered cells, but had significant effects on the elongation of adhered cells from fluorescentobservation and on the cell motility showed by the wound healing assay. The charges induced on theHA surface accelerated the cytoskeleton reorganization of the adhered cells cultured on HAspecimens. The acceleration was emerged as the cells shape, actin filament pattern such as stress fiberformation, and the prolongation of the cell movement distances
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.1055.pdf
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