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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 21 (1972), S. 109-116 
    ISSN: 1432-0533
    Keywords: Infantile Neuro-Axonal Dystrophy ; Motor End Plates ; Nerve ; Spheroïds ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The authors report the ultrastructure of neuromuscular biopsies in three cases of infantile neuro-axonal dystrophy. The presence of spheroïds in peripheral and intramuscular nerves, but also in the motor end plates allows the diagnostic of this disease, without doing cerebral biopsy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 27 (1974), S. 61-68 
    ISSN: 1432-0533
    Keywords: Muscular Pathology ; Ultrastructure ; Abnormal Muscular Inclusion ; Fingerprint Bodies ; Myofilament Synthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary “Fingerprint bodies” are added to the “atypical” formations described in diseased muscle. These subsarcolemmal inclusions are variable in size and number, not membrane-bound and are formed by fine microtubules. They are not characteristic of a specific muscular disease and occur probably along with a focal anomaly of myofilament synthesis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 109 (1970), S. 245-259 
    ISSN: 1432-0878
    Keywords: Endometrium ; Stroma cells ; Pericytes ; Blood vessels ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé L'étude du chorion cytogène de 15 endomètres humains normaux prélevés à divers moments du cycle menstruel a précisé d'importantes variations des vaisseaux et des cellules. Les vaisseaux subissent une maturation progressive: en phase proliferative moyenne, des pointes d'accroissement se forment à partir du réseau vasculaire profond activé; au milieu du cycle, elles se transforment en capillaires typiques; en phases sécrétoires moyenne et avancée, des péricytes migrent dans le chorion cytogène et se différencient en cellules choriales. Ces cellules choriales, dites fixes, ont une évolution biphasique au cours du cycle menstruel. Au milieu de chacune des phases, proliférative et surtout sécrétoire, les cellules choriales fixes, dites alors fibroblastoïdes, montrent une intense activité de synthèse. A ces périodes de synthèse succède une involution cellulaire, peu marquée en fin de phase proliferative, intense en phase sécrétoire avancée. Les cellules dites prédéciduales sont des cellules choriales fixes involuées et hyperhydratées; elles vont, en phase menstruelle, évoluer de plusieurs façons: la plupart d'entre elles régénèrent, certaines se nécrosent focalement ou totalement, d'autres font preuve d'activité macrophagique, en particulier collagénolytique.
    Notes: Summary 15 human endometria during the normal menstrual cycle have been investigated. Important alterations of the vessels and the stroma cells occur. The vessels are the site of gradual maturation. In the mid proliferative phase, growing capillaries rise from the deep-seated vascular system. In the middle of the cycle, they change into typical capillaries. In the mid and late secretory phases, pericytes leave the walls of the capillaries and differentiate into stroma cells. These stroma cells undergo a biphasic cyclic evolution. The middle of the proliferative and particularly of the secretory phase is marked by an intensive synthetic activity of the stroma cells which are called, at this time, “fibroblastoïd” stroma cells. These two periods of synthesis are followed by cellular involution, mild in the proliferative, intense in the secretory phase. The so-called predecidual cells are hyperhydrated involuted stroma cells. In the menstrual phase they behave very differently of: the majority regenerates, some predecidual cells are the site of focal or total necrosis, others show a macrophagic activity which is conspicuous in some cells having a collagenolytic activity.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 109 (1970), S. 260-278 
    ISSN: 1432-0878
    Keywords: Endometrium ; Glands ; Glycogen ; Cellular involution ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Les auteurs ont étudié les variations morphologiques et métaboliques de 15 endomètres humains normaux prélevés à diverses phases du cycle menstruel. En phase proliférative, les cellules glandulaires ont une activité métabolique de synthèse endogène et acquièrent un important complexe ergastoplasmo-golgien. En phase sécrétoire débutante le glycogène s'accumule dans les cellules glandulaires; son catabolisme fournira les réserves métaboliques nécessaires à l'intense activité de synthèse dont font preuve les cellules glandulaires en phase sécrétoire moyenne. Le matériel synthétisé, présumé mucopolysaccharidique, apparaît dans des vacuoles golgiennes qui migrent ensuite vers le pôle apical de la cellule. L'involution débute dès le 24ème jour et se traduit par la régression de l'activité de synthèse, par l'apparition de foyers autophagiques puis par une hyperhydratation cellulaire. En phase menstruelle certaines cellules se nécrosent totalement, d'autres (les plus nombreuses) régénèrent et participent à un nouveau cycle menstruel.
    Notes: Summary The authors have studied the cyclic morphologic and metabolic variations of 15 normal human endometria. In the phase of proliferation, the glandular cells have a metabolic activity of endogen synthesis and acquire welldeveloped ergastoplasm and Golgi-complexes. In the early phase of secretion, glycogen deposits appear in the glandular cells. Their catabolism will provide the metabolic reserves necessary for the intense synthesis occuring in the glandular cells during the mid secretory phase. The synthezised material — probably mucopolysaccharidic — appears first in Golgi vacuoles which migrate then towards the apical pole of the cell. The cellular involution begins on the 24th day and is characterized by the regression of the synthesis activity, by the appearance of focal necrosis and then by cellular hyperhydratation. In the menstrual phase, while some of the cells undergo total necrosis, others, the majority, regenerate and will participate in a new menstrual cycle.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 133 (1972), S. 47-57 
    ISSN: 1432-0878
    Keywords: Endometrium ; Human ; Granular stroma cells ; Relaxin ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé L'ultrastructure générale des cellules K endométriales est semblable chez l'Homme, le Rat et le Singe. Mais les granulations des cellules K humaines sont plus variées que dans ces deux dernières espèces et ont certains aspects suggérant une fonction catabolique. Etant donné cet aspect catabolique et l'existence connue d'une activité phosphatasique acide de ces cellules contenant de la relaxine, les auteurs suggèrent que les cellules K pourraient être des cellules sécrétantes en involution et ques les cellules sécrétant activement la relaxine pourraient avoir un aspect morphologique quelque peu différent de celui des cellules K.
    Notes: Summary The general ultrastructure of endometrial granular stroma cells is similar in man, rat, and monkey. But the granulations of human granular stroma cells are more various than in these two last species and have some aspects suggesting a catabolic function. With respect to this catabolic aspect and the previously shown acid-phosphatase activity of these relaxin-containing cells the authors suggest that the granular stroma cells could be involutive secretory cells and that the active relaxin-secretory cells may have some different morphological aspect.
    Type of Medium: Electronic Resource
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