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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 106 (1963), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 6 (1971), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The periodc-ntium of premolar teeth of dogs has been examined by scanning electron microscopy. lighl microscopy and microradiography. Scanning electron microscopy reveals a highly developed plexus of indifferent fibers associated with the principal fibers, The indifferent fiber plexus may be important in accomodalion of the periodontal ligament to tooth movement through anastomotie relationships between the plexus and principal fibers. Principal fibers perforate alveolar bone as compact bundles of smaller fibers. Perforating fibers of cementum enter calcified matrix as coiled or straight fibers. The number of coiled fibers is greatest in acellular cementum and the straight fibers are largest in diameter at root apices.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Recent data indicate active transport of Na+ and K+ by the main excretory duct (MED) of the rat submandibular gland. In view of these data submandibular MED's of four adult rats were investigated by transmission electron microscopy. Luminal surfaces of two MED's were examined with the scanning electron microscope. The duct is surrounded by connective tissue, blood vessels and neuron perikarya. Blood supply to the ductal epithelium consists of a plexus of sinusoidal capillaries. Three principal cell types compose the epithelium: light cells, dark cells, and basal cells. The basal cells resemble those of striated ducts except for the presence of numerous hemidesmosomes along basal plasma membranes of MED basal cells. Light cells show basal infoldings, and bulbous enlargements may occur at their distal aspects. Dark cells are narrow, electron dense cells with prominent microvilli at the luminal surface. Intercellular clefts penetrate MED epithelium from the lumen to a depth of one-third the epithelial thickness. Surfaces of the clefts are lined by dark and light cells. Intercellular tissue spaces are present at lateral boundaries of all cells and extend from the epithelial base to distal cytoplasmic levels.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 219 (1987), S. 102-107 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: This study was undertaken to test the fiber-optic perfusion fluorometer as a direct means of evaluating skin absorption and exsorption in hairless mice. Skin-barrier compromise was accomplished in the absorption experiments by application of dimethyl sulfoxide to the skin surface or by partial removal of the stratum corneum with sticky tape. Absorbed fluorescein was measured easily in unanesthetized control (skin-barrier intact) and experimental mice. Unabsorbed chemical did not fluoresce 15 minutes after application, although it was present on the surface of the skin as a dry powder. The time course of fluorescein elimination from the skin was related to a rapid phase (vascular removal) and a slow phase (reservoir entrapment).In the exsorption experiments the fluorescein was injected intraperitoneally. Back skin on the right side was swabbed with either dimethyl sulfoxide or 1% capsaicin in alcohol prior to the injections, and differences in skin fluorescence on the left (control) and right sides were recorded. One application of dimethyl sulfoxide or capsaicin increased the level of skin exsorption. Three applications of dimethyl sulfoxide almost doubled the amount of exsorbed dye, whereas three applications of the capsaicin inhibited the exsorption process.It was concluded that the fiber-optic perfusion fluorometer provides an excellent technique in support of other methods of investigating the skin.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 170 (1971), S. 357-363 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Microradiographic, polarized light, phase-contrast and scanning electron microscopic aspects of Tomes' granular layer were studied in undemineralized and demineralized premolar teeth from four dogs. The microradiographic studies show Tomes' layer to consist of a narrow zone of hypomineralized-hyperorganic dentinal matrix subjacent to the cementum. The zone appears as a series of focal points in cross sections or as an interrupted line in apico-coronal cuts through the tooth. Polarized light and phase-contrast microscopy demonstrate a morphological pattern similar to that of the microradiographs. Scanning electron microscopy suggests one component of Tomes' layer to be fibrillar. Tomes' granular layer of dog teeth may be important in protecting the tooth from sudden insults or large occlusal forces transferred to dentine via the periodontal ligament.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 111 (1962), S. 25-47 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The submaxillary glands of the adult desert rat, antelope squirrel, rat, mouse and hamster have in common low levels of amylolytic enzyme in comparison with the relatively high levels of parotid gland amylase in these rodents. Submaxillary gland acini are classed as seromucous secreting although there is some variation in the carbohydrate histochemistry of these secreting units. Granular tubules are absent in antelope squirrel submaxillary glands and they are present in the submaxillary glands of the desert rat, rat, mouse and hamster. Electron micrographs reveal the presence of numerous basal folds in the acini of antelope squirrel submaxillary and parotid glands. These structures were not observed in the salivary gland acini of the hamster. Golgi membranes and “immature” secretion granules are topographically intimate in parotid glands of the hamster and antelope squirrel. In the submaxillary glands of these two rodents, the secretory material appears to originate in relation to the endoplasmic reticulum and secondarily, the granules become associated with a diffusely arranged system of Golgi membranes. The sublingual glands of all the rodents of this study are predominantly ones that produce mucous secretion and contain well developed striated duct systems. Of the salivary glands investigated in this study, the parotid glands of the rat, mouse and desert rat produce an isotonic saliva; the saliva of the other glands is definitely hypotonic.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 132 (1970), S. 117-135 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In squirrel monkey (Saimiri sciureus) the position of submandibular glands in the neck, on either side of the trachea, more closely resembles that of rodents than that of other primates. The glands exhibit seromucous acini and mucous tubules with seromucous demilunes. Electron microscopy shows basal cytoplasmic folds and well-developed intercellular tissue spaces and canaliculi only in relation to seromucous cells. Greatly dilated cisternae of the granular endoplasmic reticulum and prominent Golgi membranes are characteristic of the mucous cells. The secretory granules of seromucous and mucous cells are morphologically distinct and indicate chemically different products for the two cell types. Histochemically, the seromucous cell shows the presence of acid mucosubstance as indicated by the PAS and Alcian blue techniques. Preliminary studies showed no appreciable quantity of amylase in submandibular glands. The intercalated duct cell is juxtaposed with the acinar cell or mucous tubule cell. Short luminal microvilli, prominent Golgi complexes and scant apical granules are notable features of intercalated duct cells. Four cell types compose the striated ducts, viz., granular light cells, agranular dark cells, vesiculated dark cells, and basal cells. Peripheral nerves are found in five different locations: in the connective tissue (interstitial), between adjacent myoepithelial and mucous-secreting cells, in the intercellular space between adjacent secretory cells, and between basal plications of striated ducts and between adjacent myoepithelial and intercalated duct cells.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 131 (1970), S. 253-275 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Submandibular glands of five adult female cats were examined by conventional electron microscopic techniques. All gland acini are mucous secreting and each acinus is capped with mucous secreting demilunar cells. Secretory product of demilunar cells is more electron lucent than that of acinar cells. The demilunes show intercellular tissue spaces and intercellular canaliculi whereas similar specializations are absent between acinar cells. Mitochondria and arrays of granular endoplasmic reticulum are more numerous in demilunar cells than in acinar cells. In acinar and demilunar cells secretory droplets first appear as enlarged Golgi saccules which subsequently become closely related to cisternae of the granular endoplasmic reticulum. Filamentous structures, interpreted as mucin molecules, are present in secretory droplets of acinar cells. Intercalated ducts are short, consisting of several junctional cells between acini and striated ducts. Striated ducts are long and tortuous and contain light cells, dark cells and basal cells. Light cells contain numerous membrane bound granules in their distal ends whereas dark cells show electron lucent vesicles in the same position. Basal cells contain a paucity of organelles and membrane plications but exhibit hemidesmosomes along their basal plasma membranes. Myoepithelial cells are abundant in relation to acinar and demilunar cells. Nerve terminals are present in some instances between acinar cells or between acinar and myoepithelial cells.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 127 (1969), S. 453-473 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Bovine parotid glands exhibit outstanding structural differences when compared with those of non-ruminant mammals. The acini are tortuous, branched and lined with cells of different heights, imparting a scalloped appearance to acinar lumina. Numerous microvilli, ca. 1.5 μ in length, extend into the lumina and intercellular canaliculi. Intercellular canaliculi measure ca. 3 μ in diameter and interweave in close association with intercellular tissue spaces. Intercellular tissue spaces are separated from the extraacinar spaces across a basal lamina only, whereas junctional complexes guard canaliculi from direct continuity with tissue spaces and/or extraacinar spaces. Flattened cytoplasmic lamellae extend from adjacent acinar cells and loosely interdigitate with one another across the tissue spaces. Acinar cells contain more mitochondria and less granular endoplasmic reticulum than parotid glands of non-ruminant mammals. Two types of secretory material, in the form of inclusions which vary in size and electron density, are present in the acinar cells. Intercalated ducts connect acini with striated ducts which in turn, empty into collecting ducts located between gland lobules. In terms of frequency of “basal infoldings” and numbers of mitochondria, striated ducts of calf parotid glands are not as well developed as those of certain other salivary glands. Myoepithelial cells are most often present at junctions of acini and intercalated ducts where they may attach to both acinar and ductal epithelium. Nerve “terminals” were not observed on the epithelial side of basement membranes in relation to the secretory cells.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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