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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 21 (1967), S. 113-119 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Virus particles with a buoyant density between 1.14 and 1.20 g/ml, with a peak density of 1.15 to 1.16 g/ml were shown to cause hog cholera disease in pigs. In electron microscopic studies particles of two distinct sizes were demonstrated in these fractions. A lipid enveloped particle with an outer diameter of 39–40 mμ and an inner (core) diameter of 28–29 mμ was proposed to be hog cholera virus.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 22 (1967), S. 467-471 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Primary SPF pig kidney cultured hog cholera virus strain PAV-1 at passages 28, 135 and 205 was studied for cytopathogenicity in PK cell cultures. No adenovirus, BVD virus or mycoplasma were demonstrated in these cultures although typical cytopathic changes developed. Cytopathic changes recorded were due to hog cholera virus infections.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 25 (1968), S. 38-51 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Characteristics of a small DNA virus isolated from kidney cell cultures of healthy 3 week-old pigs are described. The virus isolate multiplies in kidney cell cultures of pig origin, produces intranuclear inclusion bodies, and hemagglutinates guinea pig, human group 0, chicken, cat, rat and mouse red blood cells. It multiplies in pigs resulting in antibody production, but is not pathogenic for newborn hamsters and mice. The virus particle is 20–22 mμ in size, hexagonal in shape and without a lipid containing envelope. Buoyant density is between 1.37 and 1.38g/ml. This virus is stable within a wide range of pH, resistant to heat (56°C), against treatment with trypsin, and lipid solvents. The porcine virus was proposed as a member of the picodna virus group, and named “Porcine Picodna Virus (PPV)”.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The V and S antigens of bovine virus diarrhea (BVD) virus were studied by pig inoculation experiments to determine the basis for the bovine virus diarrheahog cholera heterotypic relationship. BVD virus infected tissue cultures were harvested and separated by ultracentrifugation and ultrafiltration. V antigen was prepared by Tween-ether-urea inactivation of virus. S antigen was quantitated in filtration samples and in density gradients by specific complement fixation. Pigs inoculated with crude, concentrated V antigen survived virulent hog cholera (HC) virus exposure. However, V antigen partially purified by ultracentrifugation failed to protect pigs. Neutralizing antibody to BVD, but not to HC, was synthesized in inoculated pigs following HC exposure. S antigen separated by 10 mμ, ultrafiltration and purified by potassium tartrate density gradient ultracentrifugation protected pigs from virulent HC. No BVD or HC antibody was detected at the time of HC virus exposure but HC antibody was produced at an accelerated rate following exposure. It thus appeared that an S antigen less than 10 mμ in size having a density between 1.05 and 1.10 g/ml which was produced during BVD virus replication in cells initiated the potential for a protective response.
    Type of Medium: Electronic Resource
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