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  • 1
    Electronic Resource
    Electronic Resource
    Performance of the VENUS lead-glass calorimeter at TRISTAN
    Amsterdam : Elsevier
    Nuclear Instruments and Methods in Physics Research Section A: 271 (1988), S. 432-441 
    Details
    ISSN: 0168-9002
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0168-9002(88)90302-6
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The remodelling process of allogeneic and autogenous patellar tendon grafts in rats: a radiochemical study (1996)
    Springer
    Archives of orthopaedic and trauma surgery 115 (1996), S. 10-16 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to study the remodelling of collagen fibres of transplanted tendons, one-half of the patellar tendon of the knee in 54 rats was replaced with a radioisotope (3H-proline)-labelled patellar tendon procured from a donor rat. Three transplantation models were used in this study: fresh-frozen allograft, fresh-frozen autograft (fresh-frozen isograft), and fresh autograft (fresh isograft). The percentage of old collagen was calculated as an indicator of collagen turnover from the amount of hydroxyproline and the radioactivity level of 3H-bydroxyproline in the transplanted tendons at 4, 12 and 24 weeks postoperatively. Histological evaluation was also performed at 2, 4, 12 and 24 weeks. At 4 weeks, the percentage of old collagen in the grafts from the fresh-frozen allograft group was significantly lower than in the autograft groups (20% vs. 48%). Although the percentage of old collagen in the fresh-frozen autograft group had decreased to the same level as in the fresh-frozen allograft group by 12 weeks (approximately 10%), the value was still high in the fresh autograft group at 12 weeks and remained higher (38%). Histologically, at 2 weeks, the cellularity in the fresh-frozen allograft was higher than in the fresh-frozen autograft. After 4 weeks, however, no significant difference was found between these two groups. In the fresh autograft group, the cellularity was lower than in the fresh-frozen groups at all times. In conclusion, the collagen turnover rate in the fresh-frozen allograft was the most rapid of the three transplantation models based on hydroxyproline turnover.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00453210
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of alignment of the transplanted graft extracellular matrix on cellular repopulation and newly synthesized collagen (1998)
    Springer
    Archives of orthopaedic and trauma surgery 117 (1998), S. 215-221 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study examines the effect of alignment of the transplanted graft extracellular matrix on cellular repopulation and new collagen synthesis. The lateral half of the patellar tendon was harvested as a tendon graft from Lewis rats and frozen at –80° C. In order to maintain the original alignment of the graft extracellular matrix, the graft was transplanted to a same size defect in the patellar tendon of other Lewis rats (group I). For controls, the graft was transplanted in a lax condition after excision of only the distal half of the lateral side of a patellar tendon (group II). After transplantation, six animals in each group were killed at 3, 7, 14, and 28 days. Cellular repopulation was assessed by using fibrillar-actin (F-actin) labeling with rhodamine-phalloidin, and new collagen synthesis was detected by means of a polyclonal antibody against type III collagen aminopropeptide (pN collagen III). Collagen fibril profiles were observed under the transmission electron microscope. On the 3rd day after transplantation, no specific fluorescence was detected in either group. Specific labeling for F-actin and pN collagen III, however, was observed at both ends of the graft in both groups at 1 week and throughout the graft at 2 weeks after transplantation. Consistent with the actin bundles’ orientation, pN collagen III was aligned parallel to the longitudinal axis of the graft in group I. Collagen fibrils with a smaller diameter, mixed evenly and everywhere with a larger diameter, increased gradually in group I. However, smaller collagen fibrils in group II increased more slowly and were distributed unevenly. In summary, the dense collagen arrangement in the native patellar tendon determined the alignment of the repopulating cells, and the distribution of newly synthesized collagen might be affected by the actin cytoskeleton within the repopulating cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004020050232
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Comparison of eccentric and concentric screw placement for hamstring graft fixation in the tibial tunnel (2000)
    Springer
    Knee surgery, sports traumatology, arthroscopy 8 (2000), S. 73-75 
    Details
    ISSN: 1433-7347
    Keywords: Key words Anterior cruciate ¶ligament ; Graft fixation ; Hamstrings ; Quadruple ¶semitendinosus-gracilis graft ; Tibia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Sports Science
    Notes: Abstract Interference screw fixation of four-strand hamstring grafts for ACL reconstruction has recently been introduced. By this method, the interference screw is placed in the tibial and femoral tunnels eccentric (adjacent) to the bundled limbs of the graft. In order to maximize the graft to tunnel contact to promote ¶biological fixation, it is proposed to place the screw concentrically in ¶the tunnel, in the middle of the four limbs of the graft, pressing each limb of the graft into the tunnel wall. This would be difficult to do in the proximal, folded end of the four limb graft situated in the femoral tunnel but can be done easily in the tibial tunnel. The purpose of this study was to evaluate the effect of screw placement on the stiffness, yield load, and ultimate load of hamstring graft fixation in the tibial tunnel. Five pairs of human knees were ¶used for the study. Pull out tests ¶were performed using an MTS system, pulling along the axis of the ¶tibial tunnel. Tibial fixation stiffness was greater using concentric screw placement (P 〈 0.05) although there was no statistical difference in yield load, slippage, or ultimate load.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001670050189
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    Paper (German National Licenses)
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