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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 75 (1953), S. 449-451 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Immunological reviews 166 (1998), S. 0 
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary: Studies of the ontogeny of immunity in a limited number of representative amphibians have shown that while the immune systems of the larval forms are competent to defend against potential pathogens in the temporary ponds they inhabit, they arc not equivalent to the mature immune systems that develop after metamorphosis. Metamorphosis is a critical time of transition when increased concentrations of metamorphic hormones, principally thyroid hormones (TH) and corticosteroid hormones (CH), orchestrate the loss or reorganization of many tissues and organ systems, including the immune system. Immune system reorganization may serve to eliminate unnecessary lymphocytes that could be destructive if they recognized newly emerging adult specific antigens on the adult tissues. Increased corticosteroids during metamorphosis appeal to induce apoptosis of susceptible lymphocytes. This cell death can be inhibited in vitro or in vivo by the corticosteroid receptor antagonist, RU486, A coordinate increase in both TH and CH at metamorphosis may be common to all amphibians that undergo metamorphosis. Current evidence suggests that the central hypothalamic mediator that induces pituitary production of both thyroid-stimulating hormone and adrenocorticotropic hormone in larval amphibians is corticotropin-releasing hormone. Most amphibians probably survive the temporary immunosuppression associated with metamorphosis with no deleterious effects. However, it is hypothesized that if environmental stressors result in the induction of metamorphosis at a less than optimal body size and state of immune maturation, the immune system destruction would be more significant, and the amphibians could be at greater risk of infection and death.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 392 (1982), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 4
    facet.materialart.
    Unknown
    Boston, Mass. : Periodicals Archive Online (PAO)
    Studies in Romanticism. 13:4 (1974:Fall) 299 
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  • 5
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Facilities 21 (2003), S. 168-174 
    ISSN: 0263-2772
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Architecture, Civil Engineering, Surveying
    Notes: In the year 2000, the UK government promoted the concept that hospital services be shaped around the needs of the patient to make their stay in hospital as comfortable as possible and advocated the introduction of a ward housekeeper role in at least 50 per cent of hospitals by 2004. This is a ward-based non-clinical role centred on cleaning, food service and maintenance to ensure that the basics of care are right for the patient. In 2002 the Facilities Management Graduate Centre at Sheffield Hallam University completed a series of six case studies looking at the role within different NHS Trusts. These were developed through interviews and observations with the facilities manager, ward housekeepers and nursing staff and also by collecting documentary evidence such as job descriptions, financial details and training information. Common themes were identified, relating to experiences of developing and implementing the ward housekeeper role. This paper suggests models of best practice relating to role, recruitment, induction, training, integration and management.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Facilities 17 (1999), S. 264-271 
    ISSN: 0263-2772
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Architecture, Civil Engineering, Surveying
    Notes: The study was concerned with investigating the most effective means of motivating low waged workers in the UK's private and public sectors. Levels of job satisfaction, as an indicator of work motivation, were compared between ancillary staff in the National Health Service (NHS) and the hotel and leisure industry, and correlated with the staff-centred programmes introduced in organisations for addressing the issue of staff motivation. Through empirical study no association was found between financial incentives and job satisfaction or staff motivation, and a positive correlation was found between staff-centred programmes and staff satisfaction and staff motivation, which has implications for the working practices for these workers in the NHS. These findings are placed in a theoretical context.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Facilities 19 (2001), S. 504-515 
    ISSN: 0263-2772
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Deployment and effectiveness of a series of property and facilities management (FM) policies and standards is examined from a knowledge management perspective. Does that give a better basis for effective deployment than a view of policy as driven by experts interpreting business need? A survey of the perceptions of users concerning the need for, and the deployment in practice of, standards reveals four factors which appear to correlate with the steps of the knowledge creation process suggested by Nonaka and Takeuchi. The authors believe this to be the first demonstration of FM conceptualised in such a manner. Adopting a more socially orientated approach which maximises the individual's input to the knowledge creation process, should lead to improved quality of codified knowledge, and improvement in both customer satisfaction levels and deployment in practice of standards.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Facilities 21 (2003), S. 212-222 
    ISSN: 0263-2772
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Despite rhetoric of added value, facilities management suffers a dearth of objectively researched, publicly available information concerning the impact of facilities on businesses at the level of market sectors or individual organisations. This paper aims to correct that situation for UK higher education institutions. A survey of undergraduates starting university in 2001 has confirmed, to high levels of significance, earlier research with the 2000 intake. For many institutions, facilities factors, where provided to a high standard, are perceived as having an important influence on students' choice of institution. Year-on-year comparisons show strong agreement at the global level and, where data could be gathered, at the institutional level. Individual institutions show marked differences, significant at levels of confidence of over 95 per cent. A comparison of "reputational pull" and "facilities pull" is suggested as a means of differentiating the "brand" of different institutions.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 299 (1982), S. 820-821 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We recently reported2 experiments in which eye anlagen were removed from Rana pipiens and Xenopus laevis (X. laevis and X. laevis-gilli hybrid clones3) embryos. When the enucleated embryos developed into immunocompetent larvae, they were implanted with either their own (previously parked) or an ...
    Type of Medium: Electronic Resource
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  • 10
    facet.materialart.
    Unknown
    Washington, D.C. : Periodicals Archive Online (PAO)
    Arts Education Policy Review. 8:5 (1906:Sept.) 105 
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