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  • 1
    ISSN: 0167-4943
    Keywords: Alzheimer's disease ; Growth hormone ; Metoclopramide ; Prolactin ; Vasopressin
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Archives of Gerontology and Geriatrics 15 (1992), S. 141-149 
    ISSN: 0167-4943
    Keywords: Cognitive deficit ; Institutionalized elderly ; Neuropsychological rehabilitation
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 14 (1999), S. 131-135 
    ISSN: 1432-1262
    Keywords: Key words Fecal incontinence ; Defecography ; Intraobserver agreement ; Anorectal angle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We assessed the reliability of anorectal angle (ARA) measurement as an index of fecal incontinence. The “posterior” ARA was measured at rest, squeezing, and straining in 69 continent and 82 incontinent subjects all complaining of various evacuation dysfunctions. The two groups were homogeneous with regard to sex distribution (48.6% vs. 51.4% men and 44.7% vs. 55.3% women, n.s.) and age (56.5±10.2 vs. 59.3±9.7 years, n.s.). The incidence of rectal prolapse was the same in the two groups (40 each). The intraobserver agreement index from two independent measurements (Pearson's correlation coefficient), age, and gender interaction [T 2 Hotelling test in multivariate analysis of variance (ANOVA)] and the most discriminating category of ARA measurement (Fisher's F test in ANOVA) were calculated. In addition, the relationship between ARA and severity of incontinence was assessed by the eta coefficient. Pearson's correlation coefficient was between 0.78 and 0.98 (P〈0.01). The mean ARA differed significantly between the continent and incontinent subjects (104.5±10.3° vs. 116.2±23.6° at rest, 84.5±14.2° vs. 95.1±20.1° on squeezing, and 133.7±21.7° vs. 141.7 ± 25.9° on straining; T 2 0.066, P〈0.05 in multivariate ANOVA). No interaction was noted between groups and gender (T 2 = 0.023; F = 1.11, n.s.). Resting ARA was shown by ANOVA to be the most discriminating index (F = 9.4 P〈0.01) between the two groups. Overall, ARA measurement was correlated with the severity of fecal incontinence (eta coefficient: 0.894 at rest; 0.811 on squeezing; 0.695 on straining); its accuracy was 79%, the false-positive rate was 15.3% and the false-negative rate 26.5%. Irrespective of the underlying abnormality, namely rectal prolapse, ARA measurement by defecography can: (a) be reinterpreted reliably by the same observer and (b) differentiate continent from incontinent subjects.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Techniques in coloproctology 3 (1999), S. 117-121 
    ISSN: 1128-045X
    Keywords: Key words Multiple correspondence analysis ; Chronic constipation ; Clinical decision-making
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to establish the impact of defecography on the management of patients with chronic constipation. The defecographic series of 581 patients (426 women, 155 men, mean age 51 ± 17 years) with evacuation dysfunctions was reviewed. Proper utilization of defecography was investigated by examining the structural interaction between presenting symptoms using a hierarchical log-linear model analysis. Then, to assess the impact of defecography on clinical decision-making, the multiple correspondence analysis was employed to calculate the relationship between eight radiographic findings (rectal prolapse/intussusception, rectocele, perineal descent, outlet obstruction, barium loss, delayed emptying, residue and rectal enlargement) and six clinical features (fecal blockade, provoked evacuation, tenesmus, feeling of prolapse, incontinence and mucus discharge) which occurred most frequently in the population under study. At the hierarchical log-linear analysis no more than one second-order three-symptom (i.e. fecal blockade, provoked evacuation and mucus discharge) and six first-order two-symptom interactions (including all other symptoms combined in various ways) were obtained, giving no evidence of overutilization of defecography in our constipated group. A close association (inertia, 34.4%) was found at the multiple correspondence analysis between delayed emptying, residue, outlet obstruction and rectal enlargement (relative weight 27.1%, 20.2%, 19.6% and 8.5%, respectively). Our results suggest labeling the first subdimension as the need for a conservative approach, while the second subdimension is surgery. The main value of defecography in chronic constipation is as a simple exploratory method for selecting patients who require admission to biofeedback and pelvic floor re-education.
    Type of Medium: Electronic Resource
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