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  • 1
    Electronic Resource
    Electronic Resource
    Hämangiosarkom des Herzens (1986)
    Springer
    Journal of molecular medicine 64 (1986), S. 1134-1138 
    Details
    ISSN: 1432-1440
    Keywords: Hemangiosarcoma ; Angiosarcoma ; Angioendothelioma ; Heart tumor ; Echocardiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The clinical appearance, typical localization, diagnostic procedure and the treatment of hemangiosarcoma — the most frequent malignant tumor of the heart are reported by the case of a 27 years old woman. The patient suffered from dyspnea, congestion of the superior caval vein and paroxysmal tachycardia. X-ray showed cardiac enlargement due to pericardial effusion. Echocardiography revealed a large tumor in the right atrium. Computertomography and angiocardiography showed tumor masses at the orifice of the superior caval vein and a bypass of the blood flow via the azygos vein. Thoracotomy yielded an inoperable hemangiosarcoma. By the combined treatment of irradiation and chemotherapy the cardiac tumor completely disappeared, the patient was temporary symptomless. Later metastases occured and the patient died 13 months after diagnosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01726875
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A vasopressor factor partially purified from human parathyroid glands
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 188 (1992), S. 323-329 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-291X(92)92388-E
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of diadenosine polyphosphates on Ca2+ ATPase activity (1997)
    Springer
    Journal of molecular medicine 75 (1997), S. 674-677 
    Details
    ISSN: 1432-1440
    Keywords: Key words Diadenosine polyphosphates ; Ca2+ ATPase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Diadenosine tri-, tetra-, penta-, and hexaphosphate (Ap3A, Ap4A, Ap5A and Ap6A) have been described as having various effects on vascular tone depending on the number of phosphate groups. This study examined the effect of diadenosine polyphosphates on Ca2+ ATPase activity. The activity of the enzyme was measured spectrophotometrically as the difference in hydrolysis of ATP in the presence and absence of Ca2+ with various concentrations of ATP and diadenosine polyphosphates. The diadenosine polyphosphates increased the activity of the Ca2+ ATPase. The effect tended to be stronger with Ap5A and Ap6A than with Ap3A and Ap4A in the order of potency: Ap3A≈AP4A〈Ap5A≈AP6A. The stimulatory effect of diadenosine polyphosphates was not competitive with that of ATP, suggesting an allosteric activation of Ca2+ ATPase by diadenosine polyphosphates. This effect may be physiologically relevant for limiting the increase in cytosolic free Ca2+ concentration elicited by diadenosine polyphosphates by receptor activation and modulating Ca2+ ATPase function under resting conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001090050151
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Age-dependent increase in arterial smooth muscle calcium in spontaneously hypertensive rats (1988)
    Springer
    Research in experimental medicine 188 (1988), S. 397-403 
    Details
    ISSN: 1433-8580
    Keywords: Ca2+ ; Arterial smooth muscle ; Spontaneously hypertensive rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Alterations in cellular calcium metabolism in essential hypertensive and in the SHR have been described. In the present study, particle-induced X-ray emission (PIXE) was used to get some information on the spatial distribution of Ca2+ in aortas of spontaneously hypertensive rats (SHR) and normotensive controls aged 1 week, 4 weeks, and 12 weeks. It was found that the Ca2+ content was not elevated in the aortic smooth muscle of SHR aged 1 week (n = 9) as compared to normotensive controls (n = 8) (186.8 ± 89.9 µg Ca2+/g tissue vs 254.0 ± 73.7 µg Ca2+/g tissue. The Ca2+ content was significantly raised in the aortic smooth muscle of SHR aged 4 weeks (n = 9) as compared to 4-weeks-old WKY rats (n = 12) (726.0 ± 130.4 Ca2+/g tissue vs 440.3 ± 214.4 Ca2+ µg/g tissue and in SHR aged 3 months (n = 15) as compared to WKY rats (n = 12), respectively (3317.0 ± 734.0 µg Ca2+/g tissue vs. 1632.0 ± 569.6 µg Ca2+/g tissue). The results confirm the age-related increase in the arterial Ca2+ content in normotensive rats and demonstrate additionally that this age-related rise in arterial Ca2+ content is accelerated in SHR.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851997
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    Paper (German National Licenses)
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