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  • 1
    Electronic Resource
    Electronic Resource
    Carrier-Mediated Transport of Monocarboxylic Acids in Primary Cultured Epithelial Cells from Rabbit Oral Mucosa (1997)
    Springer
    Pharmaceutical research 14 (1997), S. 320-324 
    Details
    ISSN: 1573-904X
    Keywords: oral mucosa ; carrier-mediated transport ; epithelial cells ; monocarboxylic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Purpose. Using primary cultured rabbit oral mucosal epithelial cells (ROEpi), we investigated whether carrier-mediated drug absorption via the oral mucosal route occurs. Methods. Oral mucosal epithelial cells were isolated from rabbit buccal mucosa and cultured on tissue culture plates. When the cells reached confluence, drug uptake experiments were performed. [14C]Benzoic acid or [14C] acetic acid was used as a marker for monocarboxylic acid carrier-mediated transport. Results. The uptake of [14C]benzoic acid by ROEpi occurred at a much lower rate at 4°C than at 37°C. The metabolic inhibitors, sodium azide and 2,4-dinitrophenol, significantly inhibited the uptake of [l4C]benzoic acid by ROEpi. Various monocarboxylic acids inhibited the uptake of [14C]benzoic acid or [14C]acetic acid by ROEpi, whereas dicarboxylic acids did not affect the uptake. Kinetic analysis using Lineweaver-Burk plots revealed that acetic acid competitively inhibited the uptake of [l4C]benzoic acid, and benzoic acid competitively inhibited the uptake of [l4C]acetic acid by ROEpi. Conclusions. There exists a carrier-mediated transport system for monocarboxylic acids in oral mucosal epithelial cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1012046021028
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  • 2
    Electronic Resource
    Electronic Resource
    (Z,Z)-5,27-Tritriacontadiene: Major sex pheromone ofDrosophila pallidosa (Diptera; Drosophilidae) (1994)
    Springer
    Journal of chemical ecology 20 (1994), S. 3029-3037 
    Details
    ISSN: 1573-1561
    Keywords: Drosophila pallidosa ; Diptera ; Drosophilidae ; sex pheromone ; cuticular hydrocarbon ; (Z,Z)-5,27-tritriacontadiene ; courtship behavior ; fruit fly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract A crude cuticular extract from both sexes of 3660 fruit flies (Drosophila pallidosa) was subjected to SiO2 and AgNO3/SiO2 column chromatography, accompanied by bioassay for the sex pheromone activity. After three chromatographic steps, the active fraction was obtained. The main component of the active fraction was determined to be (Z,Z)-5,27-tritriacontadiene [(Z,Z)-5,27-C33:2, on the basis of gas-liquid chromatographic analysis, chemical derivatization and gas chromatography-mass spectrometry. Synthetic (Z,Z)-5,27-C33:2 at 5 female equivalents (FE) elicited a clear courtship response with a high courtship index amongD. pallidosa males. Therefore it was concluded that (Z,Z)-5,27-C33:2 was a major sex pheromone component in this species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02033708
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  • 3
    Electronic Resource
    Electronic Resource
    Chemical Analysis and Comparison of Acid Components of Anal Secretions of Idolothripine Thrips (2000)
    Springer
    Journal of chemical ecology 26 (2000), S. 2449-2458 
    Details
    ISSN: 1573-1561
    Keywords: Idolothripinae ; Thysanoptera ; anal secretion ; thrips ; juglone ; Phlaeothripidae ; acid components ; Tubulifera
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Anal secretions of 17 species in nine genera of the subfamily Idolothripinae were analzyed by TLC, GC, and GC-MS. From all species, juglone and two or more carboxylic acids with carbon numbers ranging from 10 to 14 were detected; the exception was Gastrothrips sp., from which none was detected. Twelve carboxylic acids were found, of which decanoic acid, (E)-4-decenoic acid, and (Z)-5-tetradecenoic acid were widely found, and acid ingredients were fairly species-specific. The Gastrothrips sp. was the only exception, and it had no secretion components among the tubuliferan species so far analyzed. Juglone is thought to be a potent defensive allomone, and roles of the carboxylic acids are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005591214378
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  • 4
    Electronic Resource
    Electronic Resource
    Parasitic Wasp, Dinarmus basalis, Utilizes Oviposition-marking Pheromone of Host Azuki Bean Weevils As Host-Recognizing Kairomone (2000)
    Springer
    Journal of chemical ecology 26 (2000), S. 2677-2695 
    Details
    ISSN: 1573-1561
    Keywords: Parasitic wasp ; Dinarmus basalis ; kairomone ; host recognition ; azuki bean weevil ; Vigna angularis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract A host-recognizing kairomone responsible for the stinging behavior of the parasitic wasp, Dinarmus basalis, was studied. Fresh azuki beans coated with an acetone extract of the azuki beans, from which both emerged wasps and their host weevils were removed, elicited stinging behavior from female wasps. The kairomone is a mixture of saturated hydrocarbons and diacylglycerols, both of which are required for activity. The kairomone is composed of normal and methyl-branched hydrocarbons with carbon numbers ranging from 25 to 35, most of which are known as the hydrocarbon constituents of an oviposition-marking pheromone of the host azuki bean weevils, Callosobruchus chinensis. This indicates that D. basalis utilizes the oviposition-marking pheromone of its host weevils as a host-recognizing kairomone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026425407150
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    Paper (German National Licenses)
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