ISSN:
1434-193X
Schlagwort(e):
Tetrahydrofuran-2-ones
;
Pyrrolidin-2-ones
;
Aminations
;
Nitrosations
;
Asymmetric synthesis
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
5-Substituted (S)-tetrahydrofuran-2-ones (1a,b) and (S)-pyrrolidin-2-ones (1c,d) were transformed in three steps, by treatment with tert-butoxybis(dimethylamino)methane (Bredereck's reagent), followed by nitrosation and stereoselective catalytic hydrogenation, into the corresponding 5-substituted (3S,5S)-3-acetylaminotetrahydrofuran-2-ones (4a,b) and (3S,5S)-3-acetylaminopyrrolidin-2-ones (4c,d).
Materialart:
Digitale Medien
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