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  • 1
    ISSN: 1365-2214
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Cystic fibrosis (CF) is a progressive disease with no known cure. Advances in diagnosis and treatment have resulted in patients living longer and thus families live with the illness for longer. Treatments are becoming increasingly demanding and are largely performed in the family home. Mothers are often reported to experience greater stress and poorer adjustment than mothers of well children or population norms. Patients and siblings are also reported to display adjustment difficulties. Siblings have rarely been included in research designs. This qualitative study investigates the impact of CF and treatment on eight patients, eight mothers, one father and eight siblings. A family systems perspective was adopted. Each individual was interviewed independently using semistructured interviews. Patients and siblings were aged between 9 and 21 years. Qualitative analyses revealed high levels of non-adherence (intentional and unintentional) and parental involvement in treatment, minimal involvement of siblings, and preferential treatment towards patients. Demanding treatment, coupled with the progressive nature of CF, promote high levels of parental involvement for younger children as well as older teenagers, often due to attempted or actual non-adherence. Siblings may receive less attention while patients' needs take priority. Future development of a measure of adherence suitable for children and adolescents should take into account different motivations for non-adherence, particularly regarding the level of personal control over adherence to treatment. In addition, the potential impact of having a brother or sister with CF should not be underestimated and the needs of siblings should not go unnoticed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 425 (1984), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Zusammenfassung Untersuchungen von Zusammensetzungen von Einzelkörnern und benachbarten Körnern mit der Mikrosonde und durch erzmikroskopische Studien an gediegenem Gold weisen beträchtliche Variationen in der primären Verteilung von Silber auf. Die Goldkörner enthalten von 1–55 Gewichtsprozent Silber; Kupfer ist gegenwärtig in Körnern von nur einer Gegend zwar in Mengen von 0,1–0,6 Gewichtsprozent. Manche Goldkörner sind stark zonar mit Silber während andere keine bemerkbaren Zonen aufweisen. Goldkörner aus einigen Ablagerungen zeigen eine bemerkenswerte Homogenität von Silberund/oder Kupfergehalt, andere aber sind durch extreme Inhomogenität gakennzeichnet. Wir glauben, daß die festgestellten Inhomogenitäten und Variationen des Silbergehaltes Merkmale von primären Ablagerungen sind. Zusätzlich wurden an vielen von den von uns untersuchten Körnern scharfbegrenzte Randzonen mit niedrigem Silbergehalt beobachtet. Wir glauben, daß sich die Randzonen in einer verhältnismäßig oxidierenden Umgebung von niedriger Temperatur entwickelten und daß sie nicht Merkmale primärer Erzadern sind. Opake Mineraleinschlüsse von primärem Ursprung in Goldkörnern kommen in manchen Ablagerungen vor, selten in vielen und sind virtuell abwesend in anderen. Für einige Goldablagerungen können diese Einschlüsse als charakteristische Kennzeichen von Wert sein. Der niedrigste Silbergehalt für die meisten Goldkristalle, aus dem Copper Basin, Arizona, war in der Mitte der Körner und der höchste Silbergehalt war in den Randzonen der Körner gegenwärtig. Es wird angenommen daß dieses auf eine Zunahme in den Proportionen von Silber zu Gold in der Lösung während des Wachstums der Kristalle zurückzuführen ist. Analysen von Größensortierungen von 331 Goldkörnern aus den Pennsylvania Mountain, Colorado, zeigen keine systematische Korrelation der Korngrößen mit den Silbergehalten. Mikrosonde — Scanninganalysen an Gold aus dem Alder Gulch, Montana, weisen auf mehr als einen Mineralisationsvorgang hin. Pyrit- und Akanthiteinschlüsse von weniger als 0,05 mm in den größten Dimensionen sind in einigen Körnern dieser Ablagerung enthalten. Einschlüsse von Pyrit, Pyrrhotin, Chalcopyrit und von einem isotropen Co-As-S-mineral finden sich in dem silberarmen, kupferhaltigen Gold von Ninemile Creek, Montana. Der Kupfergehalt und der niedrige Silbergehalt in diesem Gold sind nicht typisch für die in dem westlichen Teil der USA übliche Gold-Quarz-Pyrit Assoziation.
    Notes: Abstract Electron-microprobe analyses and mineragraphic studies of native gold demonstrate considerable variations in the primary intergrain and intragrain distribution of silver. The gold grains have from 1–55 weight percent silver; copper is present in grains from only one locality and ranges from 0.1–0.6 weight percent. Some gold grains have strong zoning of silver whereas others have no detectable zoning. Gold grains from some deposits show remarkable intergrain homogeneity of silver and/or copper content, but others exhibit extreme heterogeneity. We believe that the inhomogeneities and variations in silver content recognized and emphasized here are features of primary deposition. We also recognize low-silver rims with sharp boundaries bordering many of the grains examined but believe these are developed in a relatively oxidizing, low-temperature environment and are not primary lode features. Opaque mineral inclusions of primary origin in gold grains are common in some deposits, scarce in many, and virtually absent from others. These inclusions may be of value in characterizing some gold deposits. For the majority of gold crystals from Copper Basin, Arizona, the lowest silver content observed was in the central portion of each grain and the highest silver content was in the rim. This is believed to be due an increase in the proportion of silver to gold in solution during growth of the crystals. Analysis of sized fractions of 331 gold grains from Pennsylvania Mountain, Colorado, shows no systematic correlation of grain size with silver content. Electron microprobe step-scanning of gold from Alder Gulch, Montana, suggests more than one mineralization event took place. Pyrite and acanthite inclusions less than 0.05 mm in the largest dimension, are present in some grains from this deposit. Inclusions of pyrite, pyrrhotite, chalcopyrite, and an isotropic Co-As-S mineral are present in the low-silver, copper-bearing gold from Ninemile Creek, Montana. The presence of copper and the low silver content in this gold is not typical of the gold-quartz-pyrite association which is common in the Western United States.
    Type of Medium: Electronic Resource
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  • 4
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    London : Periodicals Archive Online (PAO)
    Journal of adolescence. 15:4 (1992) 449 
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 255-265 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto È stata sfruttata la risoluzione spaziale del sensore magnetico per fornire stime numeriche del contributo atriale ai campi magnetici registrati esattamente prima della depolarizzazione ventricolare. Si trova che il contributo è piccolo, e questo rafforza l’interpretazione originale secondo la quale questi campi derivano principalmente dal sistema di conduzione del cuore.
    Notes: Summary We have exploited the spatial resolution of the magnetic sensor to provide numerical estimates of the atrial contribution to magnetic fields recorded just prior to ventricular depolarization. The contribution is found to be small, strenghening our original interpretation that such fields originate mostly in the conduction system of the heart.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è sviluppato un metodo magnetico per misurazioni dirette non invasive del ferro di immagazzinamento epatico umano con uno suscettometro SQUID. Le determinazioni magneticain vivo e chimicain vitro del ferro epatico non eme sono strettamente correlate. Le misurazioni magnetiche dei depositi di ferro sono utili, dal punto di vista clinico, nella diagnosi dei disordini nel metabolismo del ferro.
    Notes: Summary A magnetic method for direct noninvasive measurements of human hepatic storage iron with a SQUID susceptometer has been developed.In vivo magnetic andin vitro chemical determinations of liver nonheme iron are closely correlated. Magnetic measurements of iron stores are clinically useful in the diagnosis of disorders of iron metabolism.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 582-593 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Questo lavoro descrive un nuovo suscettometro SQUID a doppio canale coadiuvato da computer destinato a raggiungere stime accuratein vivo delle concentrazioni di accumulo di ferro nei tessuti. Si discutono le considerazioni pratiche dello schema, la funzionalità sperimentale al rumore e la risoluzione clinica anticipata del nuovo sistema.
    Notes: Summary This paper describes a new computer-enhanced dual-channel SQUID susceptometer designed to achieve accuratein vivo estimates of tissue storage iron concentrations. We discuss the practical design considerations, instrumental noise performance and anticipated clinical resolution of the new system.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 505-511 
    ISSN: 0392-6737
    Keywords: Biomagnetism (including magnetocardiography) ; Superconducting devices ; superconducting magnets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si è studiato il campo magnetico prodotto dal cervello prendendo in considerazione una varietà di eventi rari. Si riporta il carattere temporale della risposta a un raro stimolo uditivo. Il campo magnetico appare offrire un’utile nuova sonda dell’attività endogena nel cervello umano.
    Notes: Summary We have studied the magnetic field produced by the brain when attending to a variety of rare events. The temporal character of the response to a rare auditory stimulus is reported. The magnetic field appears to offer a useful new probe of endogeneous activity in the human brain.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es zeigte sich, daß das für Neugeborene empfohlene Dosierungsschema für Amikacin von 15 mg/kg/Tag bei vier Neugeborenen nicht zufriedenstellend war und eine Anfangsdosis von 10 mg/kg bei zwei weiteren Neugeborenen mit normaler Nierenfunktion nicht zu einer Verbesserung der Spiegel führte. Vierzehn Neugeborene erreichten mit 20 mg/kg/Tag zufriedenstellende Spiegel; die Spitzenwerte betrugen 21,5±4,5 µg/ml und die mittleren Spiegel lagen bei 3,34±2,05 µg/ml. Die Maxima wurden zwischen 17 und 60 Minuten erreicht und wechselten mit der verabreichten Dosis. Die Halbwertszeit stand in Relation zu Plasmacreatinin, Harnstoff, Lebensalter und Gewicht. Dreizehn Neugeborene mit vorbestehender Nierenstörung konnten wir durch Änderung des Dosierungsintervalls oder der verabreichten Dosis behandeln. Nebenwirkungen beschränkten sich auf Eosinophilie bei sechs Kindern. Zeichen für eine ausgesprochene Nephrotoxizität oder erhebliche Störungen des achten Hirnnerven konnten nicht festgestellt werden.
    Notes: Summary The recommended neonatal dosage regime for amikacin of 15 mg/kg/day was found to be unsatisfactory in four neonates and a loading dose of 10 mg/kg did not improve levels in two further newborns with normal renal function. Fourteen neonates on 20 mg/kg/day regime achieved satisfactory levels; peak values were 21.5±4.5 µg/ml and trough levels 3.34±2.05 µg/ml. Peak time ranged from 17 to 60 minutes and varied with the dose given. The half-life was related to plasma creatinine, urea, post-natal age and weight. Thirteen neonates with pre-existing renal impairment were managed by alteration of dosage interval or quantity given. Side-effects were confined to eosinophilia in six infants, and no definite nephrotoxicity or gross eighth nerve damage was demonstrated.
    Type of Medium: Electronic Resource
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