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  • 1
    Electronic Resource
    Electronic Resource
    Leucocytoclastic vasculitis associated with mixed cryoglobulinaemia and hepatitis C virus infection (1997)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 136 (1997), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Mixed cryoglobulinaemia is frequently associated with chronic hepatitis. We report a patient with mixed cryoglobulinaemia, hepatitis C virus (HCV) infection and palpable purpura. The skin manifestations were diagnosed as leucocytoclastic vasculitis in view of both the clinical appearance and the histological findings. In this study, we demonstrated the presence of IgG–class anti–HCV–antibody. HCV–RNA and IgA–class rheumatoid factor in the cryoprecipitate. These results suggest that the cryoglobulinaemia in this case was caused by aggregation of an immune complex comprised of HCV and anti–HCV antibody with IgA–type–rheumatoid factor, and that this led to a cutaneous vasculitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1997.d01-1186.x
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  • 2
    Electronic Resource
    Electronic Resource
    Impact ionization model for full band Monte Carlo simulation (1994)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 75 (1994), S. 3500-3506 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The impact ionization rate in silicon is numerically derived from wave functions and energy band structure based on an empirical pseudopotential method. The calculated impact ionization rate is well fitted to an analytical formula with a power exponent of 4.6, indicating soft threshold of impact ionization rate, which originates from the complexity of the Si band structure. The calculated impact ionization rate shows strong anisotropy at low electron energy (cursive-epsilon〈3 eV), while it becomes isotropic at higher energy. Numerical calculation also reveals that the average energy of secondary generated carriers depends linearly on the primary electron energy at the moment of their generation. A full band Monte Carlo simulation using the newly derived impact ionization rate demonstrates that calculated quantum yield and ionization coefficient agree well with reported experimental data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.356112
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  • 3
    Electronic Resource
    Electronic Resource
    New densimeter for cryogenic fluids by magnetic levitation of a high-Tc superconductor (1988)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 59 (1988), S. 2539-2543 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new magnetic densimeter for cryogenic fluids has been developed by adapting a magnetic levitation of a high-Tc superconductor. In this instrument, a superconducting material made of Y–Ba–Cu–O is sealed in a hollow glass buoy, and a stable levitation of the buoy is carried out with the Meissner effect of the superconductor simply by placing the buoy in the fluid above a ring-shaped permanent magnet. The fluid density is obtained from the magnetic force required to levitate the buoy in the fluid. To measure this force, the magnet is suspended from an electronic balance and the reaction force acting on the magnet is determined directly as a change of the apparent weight of the magnet. Details are given of the theoretical calculation of the force acting on the superconductor in the magnetic field and of the construction of the apparatus. The measurements of the saturated liquid density of nitrogen have shown a standard deviation of 0.014%. The total uncertainty of the measurements is estimated to be less than 0.06%. The results agree with reliable literature values within the experimental uncertainty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139894
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  • 4
    Electronic Resource
    Electronic Resource
    Time change in the maximum of scattering intensity during spinodal decomposition (1989)
    s.l. : American Chemical Society
    Macromolecules 22 (1989), S. 4663-4664 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00202a053
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  • 5
    Electronic Resource
    Electronic Resource
    A Monte Carlo simulation of anisotropic electron transport in silicon including full band structure and anisotropic impact-ionization model (1994)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 75 (1994), S. 297-312 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The physics of electron transport in bulk silicon is investigated by using a newly developed Monte Carlo simulator which improves the state-of-the-art treatment of hot carrier transport. (1) The full band structure of the semiconductor was computed by using an empirical-pseudopotential method. (2) A phonon dispersion curve was obtained from an adiabatic bond-charge model. (3) Electron-phonon scattering was computed by using a rigid pseudo-ion model. The calculated scattering rate is consistent with the full band structure and the phonon dispersion curve of silicon, thus leaving no adjustable parameters such as deformation potential coefficients. (4) The impact-ionization rate was calculated by using Fermi's golden rule directly from the full band structure. We took into account the dielectric function depending on both wave vector and transition energy in the numerical calculation of the rate. The impact-ionization rate obtained in the present study strongly depends on both wave vector and band index of the conduction electron, which is ignored by the traditional Keldysh formula. (5) In the simulator, the final state of a scattering electron is determined in such a way as to conserve both energy and momentum in scattering processes. The simulated results, under the steady-state conditions as well as under the nonequilibrium conditions, are presented and compared with experimental results. Special attention is focused on anisotropic transport during velocity overshoot. Quantitative agreement between calculated and experimental results confirms the validity of the newly developed Monte Carlo simulator and the physical models that were used.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.355849
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  • 6
    Electronic Resource
    Electronic Resource
    Posttransplant IgA nephropathy: A clinicopathological study in comparison with IgA nephropathy in native kidney (1999)
    Melbourne, Australia : Blackwell Science Asia Pty. Ltd.
    Nephrology 5 (1999), S. 0 
    Details
    ISSN: 1440-1797
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1440-1797.1999.00093.x
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  • 7
    Electronic Resource
    Electronic Resource
    Tumour necrosis factor-α but not interferon-γ is the main inducer of inducible protein-10 in skin fibroblasts from patients with atopic dermatitis (2004)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 150 (2004), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Inducible protein (IP)-10 belongs to the CXC chemokine subfamily and acts through the CXCR3 receptors that attract T lymphocytes. Keratinocytes are thought to be the main cell source of this chemokine in the skin, but other sources need to be elucidated.Objectives  To determine whether skin fibroblasts, besides keratinocytes, are able to produce IP-10 and the possible involvement of these cells in pathogenesis of atopic dermatitis (AD).Methods  We studied the production pattern of IP-10 in dermal fibroblasts obtained from healthy donors, AD patients and in the HaCaT cell line (normal human keratinocytes) used as control. We stimulated fibroblasts after the sixth and seventh passage with tumour necrosis factor (TNF)-α, interferon (IFN)-γ, interleukin (IL)-4, and by means of reverse transcriptase–polymerase chain reaction and enzyme-linked immunosorbent assay analysis detected the production pattern of IP-10. To determine whether a different pattern of production of IP-10 by fibroblasts corresponds to the level of this chemokine in the plasma of patients with AD, we also checked the plasma IP-10 levels in 33 AD patients and 10 healthy donors.Results  The pattern of chemokine production between dermal fibroblasts and HaCaT cells was different. The main inducer of IP-10 in fibroblasts was TNF-α, whereas IFN-γ was the main inducer of IP-10 in HaCaT cells. We demonstrate that fibroblasts from AD patients have higher IP-10 expression and are more sensitive to TNF-α stimulation compared with healthy controls. Consequently, IP-10 levels in plasma of AD patients were higher than in healthy donors.Conclusions  Skin fibroblasts could be an important source of IP-10. TNF-α is the main inducer of IP-10 by skin fibroblasts, but not IFN-γ or IL-4. The increased level of IP-10 in the plasma of patients with AD could be connected with increased activity of skin fibroblasts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.05937.x
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  • 8
    Electronic Resource
    Electronic Resource
    Impaired sweating function in adult atopic dermatitis: results of the quantitative sudomotor axon reflex test (2002)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 147 (2002), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Background Impaired sweating is thought to be a cause of barrier dysfunction in atopic dermatitis (AD). Objectives To examine the sweating function in AD in a quantitative manner. Methods We investigated the sweating response of lesional and non-lesional skin of adult patients with AD by a quantitative sudomotor axon reflex test in which the axon reflex is stimulated by acetylcholine iontophoresis. Sweat volume on the volar aspect of the forearm was measured in 18 adult patients with AD and in 40 non-atopic controls; five patients with Sjögren's syndrome were also studied as disease comparators. We also evaluated the sweating function in four AD patients after topical corticosteroid therapy. Latency time, direct (DIR) sweat volume and axon reflex-mediated indirect (AXR) sweat volume were the variables studied. Results The latency time in AD patients was significantly prolonged and AXR sweat volume significantly reduced compared with those in non-atopic control subjects. The latency time and AXR sweat volume of lesional AD skin were significantly more prolonged and reduced, respectively, than those of non-lesional skin. In contrast, the DIR sweat volume of lesional or non-lesional AD skin induced by direct stimulation with acetylcholine was only slightly reduced when compared with that in non-atopic controls. Latency time and sweat volumes of lesional and non-lesional AD skin improved after topical corticosteroid therapy. Conclusions These results suggest that the impaired sweat response in AD is attributable to an abnormal sudomotor axon reflex, which is reversed by topical corticosteroid administration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2002.04765.x
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  • 9
    Electronic Resource
    Electronic Resource
    Expression of liver type pyruvate kinase in insulinoma cells: Involvement of LF-B1 (HNF1)
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 181 (1991), S. 259-264 
    Details
    ISSN: 0006-291X
    Keywords: [abr] PK; pyruvate kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0006-291X(05)81411-1
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  • 10
    Electronic Resource
    Electronic Resource
    Effect of calcium channel agonist bay K 8644 on calcitonin secretion from a rat C-cell line
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 130 (1985), S. 454-459 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-291X(85)90438-3
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