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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of natural products 49 (1986), S. 466-469 
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of natural products 51 (1988), S. 504-508 
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Advances in science and technology Vol. 49 (Oct. 2006), p. 258-262 
    ISSN: 1662-0356
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Natural Sciences in General , Technology
    Notes: In the treatment based on Guided Bone Regeneration method (GBR), membranes arenecessary to cover bone defects and prevent the invasion of surrounding soft tissues. In spite of thepotential usefulness of GBR method, no appropriate materials for the membrane have beendeveloped and this method is not utilized frequently in common clinical practice. Here wedeveloped materials such as a composite of β-tricalcium phosphate (β-TCP) and copolymer ofL-lactide, glycolide and ε-caplolactone (PLGC), and designed the novel GBR membranes with idealmechanical properties. The materials had good biocompatibility, and the membrane had sufficientstrength although their thickness was as thin as 200 μm. The membranes were applied to large bonedefects created in canine mandibular bones, and significant enhancement in bone regeneration wasdemonstrated
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 534-536 (Jan. 2007), p. 369-372 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The production method of micro sacrificial plastic mold insert metal injection molding,namely μ-SPiMIM process has been proposed to solve specific problems involving theminiaturization of MIM. The sacrificial plastic mold (SP-mold) with fine structures was prepared byinjection-molding polymethylmethacrylate (PMMA) into Ni-electroform, which is a typical LIGA(Lithographie-Galvanoformung-Abformung) process. Stainless steel 316L feedstock was injectionmoldedinto the SP-mold which had micro structures with multi-pillars. The green compact wasdemolded as one component with the SP-mold, which was decomposed along with binderconstituent of feedstock in debinding process. This study focused on the effects of metal particlesize and processing conditions on the shrinkage, transcription and surface roughness of sinteredparts, which were evaluated by SEM (Scanning Electron Microscope) observation
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 3667-3672 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, gas nitriding was processed for various sizes of Ti specimens which wereproduced by metal injection molding (MIM) process, for the sake of enabling the high functionality atlow processing cost. It was shown by the nitriding treatment that the hardness of the surface increasedextremely and the microstructure changed to the TiN and acicular α-Ti phase. With respect to theeffect of the nitriding on the size of parts, micro dumbbell specimen had around five times highercontent of nitrogen than the block ones. It was suggested that the size of μ-MIM products is so smallthat the surface treatment can contribute significantly to improve the properties, and then gas nitridingprocess may be one of effective surface treatment methods for high functionality of μ-MIM Tiproducts
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 534-536 (Jan. 2007), p. 981-984 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A novel production method for porous metal components has been developed byapplying powder space holder (PSH) method to metal powder injection molding (MIM) process.The PSH-MIM method has an industrial competitive advantage that is capable of net-shapemanufacturing the micro-sized porous metal products with complicated shapes and controlledporosity and pore size. In this study, the small impeller with homogeneous micro-porous structurewas manufactured by the PSH-MIM method using porous compounds composed of fine stainlesssteel 316L powder and polymethylmethacrylate (PMMA) particle. The effects of combinations insize and fraction of PMMA particle on dimensional tolerance and variation of sintered porousspecimens were investigated. It was concluded that the PSH-MIM method could manufacturecommercially micro-porous metal components with high dimensional accuracy
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 534-536 (Jan. 2007), p. 361-364 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Gas surface treatment is considered to be especially effective for Titanium because of itshigh reactivity. In this study, we investigated the gas nitriding mechanism in titanium sintered partsproduced by metal powder injection molding (MIM) process. In MIM process, gas nitriding can besurface-treated subsequently after debinding and sintering process. Then, the microstructure andnitrogen content of sintered MIM parts are considered to be greatly influenced by not only nitridingconditions but also sintered conditions. In this study, the effects of sintering time on microstructuresuch as nitrided layer thickness and hardness was investigated. Focus was given to the effects ofspecimen size on nitriding process, because the size of micro metal injection molding (μ-MIM)product is so small and the specific surface of that product is so large that the mechanical andfunctional properties can be subject to change by nitriding
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 534-536 (Jan. 2007), p. 381-384 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This study aims to investigate the effects of hybrid micro/nano powders in a micro metalinjection molding (μ-MIM) process. A novel type of mixing-injection molding machine was used toproduce tiny specimens (〈1mm in size) with high trial efficiency using a small amount of feedstock(〈0.05cm3 in volume). Small dumbbell specimens were produced using various feedstocks preparedby changing binder content and fraction of nano-scale Cu powder (130nm in particle size). Theeffects of adding the fraction of nano-scale Cu powder on the melt viscosity of the feedstock,microstructure, density and tensile strength of sintered parts were discussed
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 745-750 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: One of the authors proposed a non-equilibrium powder metallurgy process, whichenables the fabrication of a near net-shape product using TiC and TiN/Silicide ceramic composites.The PM process in combination with mechanical alloying (MA) and Spark Plasma Sintering (SPS)are applied to produce nano-grain composite, TiC/Ti5Si3. Powders of elements Ti and SiC whosecomposition is Ti-20 mass%SiC are blended for MA. After the alloying, the MA powder whoseaverage particle size is 20~30 μm, has amorphous-like structures, and then the MA powder iscompacted by SPS. Results of compression-tests indicate the occurrence of unusual hightemperaturedeformation behaviors such as low flow stress at the lower deformation temperature orat the high initial strain rates were observed in the SPS compacts. TEM observations of thedeformed compacts after the compression-tests indicate the microstructure has no-strain equiaxial -grains and clear boundaries. This serves as proof of a superplasticity deformation. In addtion, theresults of the XRD analysis of the compressed-compacts show that new phases are formed duringthe compression-test. Therefore, the above deformation is attributed to a "pseudo" superplasticity inwhich the phase transition of metastable microstructure occurs during the deformation
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: AF in Mitral Valve Disease. Introduction: Patients with mitral valve disease frequently have atrial fibrillation (AF), and the left atrium is presumed to be the primary atrium that develops AF. However, it is still not clear whether the electrophysiologic abnormalities responsible for AF are confined to the left atrium in this subset of patients. Methods and Results: To examine the AF vulnerability of each atrium, we measured the wavelength and in homogeneity of the conduction at the lateral right atrium, lateral left atrium, and Bachmann's bundle after defibrillation of AF in seven patients undergoing the maze procedure and mitral valve surgery for AF and isolated mitral valve disease, respectively (AF group). The data were compared with five coronary surgery patients in sinus rhythm (SR group). The wavelength in the AF group was significantly shorter (P 〈 0.05) than in the SR group not only at the lateral left atrium (225 ± 62 vs 285 ± 36 mm) but also at the lateral right atrium (214 ± 54 vs 254 ± 34 mm). The variation coefficient of the local maximum activation phase difference in the AF group (1.9 ± 0.8 at the right atrium, 2.1 ± 0.8 at the lateral left atrium, and 2.0 ± 0.6 at Bachmann's bundle) was significantly greater (P 〈 0.05) than in the SR group at all atrial regions. Conclusion: AF vulnerability was not confined to the left atrium immediately after defibrillation in AF patients with isolated mitral valve disease. Electrical remodeling resulting from perpetuation of AF, pathological changes extending to the right atrium, geometric changes caused by the atrial interactions occurring across the interatrial septum, or a combination of these may explain the results.
    Type of Medium: Electronic Resource
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